胸膜实质纤维弹性组织增生症伴下叶普通型间质性肺炎急性加重：一例尸检病例
Acute exacerbation of pleuroparenchymal fibroelastosis with lower lobe usual interstitial pneumonia: An autopsy case.
作者信息
Matsumura Takuma, Makino Takashi, Yagisawa Marie, Ishige Masaki, Akimoto Yuto, Ito Kosuke, Anami Yoichi, Kono Masakazu
机构信息
Department of Respiratory Medicine, Tokyo Rosai Hospital, 4-13-21, Ohmori-Minami, Ohta-ku, Tokyo, Japan.
Department of Respiratory Surgery, Tokyo Rosai Hospital, 4-13-21, Ohmori-Minami, Ohta-ku, Tokyo, Japan.
出版信息
Respir Med Case Rep. 2023 Apr 7;43:101846. doi: 10.1016/j.rmcr.2023.101846. eCollection 2023.
An 87-year-old man presented with dyspnea. Computed tomography revealed progressive subpleural consolidation in the apex, reticular shadows in the lower lobes, and bilateral ground glass opacifications. He died of respiratory failure on day 3. The post-mortem examination showed exudative stage diffuse alveolar damage and pulmonary edema. Intraalveolar collagenous fibrosis and subpleural elastosis were observed in the upper lobes, accompanied by interlobular septal and pleural thickening and lung architecture remodeling in the lower lobes. He was diagnosed with acute exacerbation of pleuroparenchymal fibroelastosis with lower lobe usual interstitial pneumonia, which can be fatal.
一名87岁男性因呼吸困难就诊。计算机断层扫描显示肺尖部进行性胸膜下实变、下叶网状阴影以及双侧磨玻璃样混浊。他在第3天死于呼吸衰竭。尸检显示渗出期弥漫性肺泡损伤和肺水肿。上叶可见肺泡内胶原纤维化和胸膜下弹性组织变性，同时下叶伴有小叶间隔和胸膜增厚以及肺结构重塑。他被诊断为胸膜实质纤维弹性组织增生症急性加重伴下叶普通型间质性肺炎，这可能是致命的。
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