耐氨苄西林的不可分型菌引起的绒毛膜羊膜炎和早期妊娠丢失
Chorioamnionitis and early pregnancy loss caused by ampicillin-resistant non-typeable .
作者信息
Nishihara Yuji, Hirai Nobuyasu, Sekine Takahiro, Okuda Nao, Nishimura Tomoko, Fujikura Hiroyuki, Furukawa Ryutaro, Imakita Natsuko, Fukumori Tatsuya, Ogawa Taku, Suzuki Yuki, Nakano Ryuichi, Nakano Akiyo, Yano Hisakazu, Kasahara Kei
机构信息
Center for Infectious Diseases, Nara Medical University, Shijo-cho, Kashihara, Nara, Japan.
Department of Microbiology and Infectious Diseases, Nara Medical University, Shijo-cho, Kashihara, Nara, Japan.
出版信息
IDCases. 2023 Mar 29;32:e01751. doi: 10.1016/j.idcr.2023.e01751. eCollection 2023.
can cause intra-amniotic infection and early pregnancy loss. The mode of transmission and risk factors for uterine cavity infections are unknown. Here, we present the case of chorioamnionitis caused by ampicillin-resistant in a 32-year-old Japanese woman at 16 weeks of gestation. Despite empirical treatment, including ampicillin, as recommended by the current guidelines, she had fetal loss. The antimicrobial regimen was changed to ceftriaxone, and the treatment was completed without complications. Although the prevalence and risk factors for chorioamnionitis caused by ampicillin-resistant are unknown, clinicians need to recognize as a potentially drug-resistant and lethal bacterium for pregnant women.
可导致羊膜腔内感染和早期妊娠丢失。子宫腔感染的传播方式和危险因素尚不清楚。在此，我们报告一例32岁日本女性在妊娠16周时由耐氨苄西林菌引起的绒毛膜羊膜炎病例。尽管按照当前指南的建议进行了包括氨苄西林在内的经验性治疗，但她仍发生了胎儿丢失。抗菌治疗方案改为头孢曲松，治疗完成且无并发症。虽然耐氨苄西林菌引起的绒毛膜羊膜炎的患病率和危险因素尚不清楚，但临床医生需要认识到该菌对孕妇来说是一种潜在的耐药且致命的细菌。
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