Rivera Paola A, Gupta Akash, Kombo Ninani
Department of Ophthalmology and Visual Science, School of Medicine, Yale University, New Haven, CT, USA.
Department of Medicine, School of Medicine, Yale University, New Haven, CT 06510, USA.
Ther Adv Ophthalmol. 2023 Feb 13;15:25158414231152761. doi: 10.1177/25158414231152761. eCollection 2023 Jan-Dec.
Retinal vasculitis (RV) refers to an entity in which the retinal vasculature is inflamed, frequently with indications of inflammation elsewhere in the eye. Non-infectious RV can be idiopathic or associated with systemic disease, ocular conditions, and malignancy. It can also be classified based on the vessel affected: artery, vein, or both. Due to the lack of strong evidence-based treatment trials and algorithms for RV, physicians must often rely on their experience, which creates great variability in treating this entity. This article provides an overview of various treatment modalities used in the management of non-infectious RV, with a focus on immunomodulatory therapies. We outline a potential stepwise approach of starting with steroids to control the acute inflammation and subsequently changing to immunomodulatory therapy (IMT) for long-term treatment.
视网膜血管炎（RV）是指视网膜血管发生炎症的一种病症，通常眼部其他部位也有炎症迹象。非感染性RV可为特发性，或与全身性疾病、眼部疾病及恶性肿瘤相关。它也可根据受累血管进行分类：动脉、静脉或两者皆有。由于缺乏针对RV的强有力的循证治疗试验和方案，医生常常依赖自身经验，这导致在治疗该病症时存在很大差异。本文概述了用于非感染性RV治疗的各种方法，重点是免疫调节疗法。我们概述了一种潜在的逐步治疗方法，即先使用类固醇控制急性炎症，随后改用免疫调节疗法（IMT）进行长期治疗。
