Rumeli University, Private Safa Hospital, İstanbul, Turkey.
Actas Urol Esp (Engl Ed). 2023 Mar;47(2):78-86. doi: 10.1016/j.acuroe.2022.08.014. Epub 2022 Aug 10.
The bulbar urethra is the location where urethral stricture is most commonly observed. The most successful method for long and recurrent urethral stenosis is graft urethroplasty. The most successful graft source is buccal mucosa, with advantages like easy adaptation to the corporeal bed, thick epithelium, thin lamina propria with rich vascular structure and easy ability to obtain the graft. In this study we aimed to retrospectively assess the outcomes and predictive factors affecting surgical success of our buccal mucosal graft urethroplasty surgery performed for bulbar urethra stenosis with moderate length.
In this study, we monitored 51 patients with mean 4.4 cm bulbar urethral stricture length for mean 17 months follow-up. From operative and postoperative data, stenosis length, operation duration, Qmax, International Prostate Symptom Score, International Index of Erectile Function-Erectile Function and OF, success rates in total and in subgroups (age, according to DVIU, etiology, BMI and DM), follow-up duration, complications, re-stricture time and number were assessed.
The total success of the operations was 86.3%. In 17 months, the re-stricture rate was 13.7%. Oral and urethral complications were all minor. The complications with longest duration (6 months) were ejaculation, erection problems and urethral fistula. Mean time to re-stricture was 11 months. All re-stricture patients were relieved by one DVIU session each.
For bulbar urethral stricture longer than 2 cm and with recurrence, the dorsal buccal mucosa graft replacement is a very successful method with low complication rates.
球部尿道是最常发生尿道狭窄的部位。对于长段且反复发作的尿道狭窄,最有效的治疗方法是移植物尿道成形术。最成功的移植物来源是颊黏膜,具有易于适应体部床、厚的上皮、薄的固有层伴丰富的血管结构和易于获取移植物等优点。本研究旨在回顾性评估我们采用颊黏膜移植物尿道成形术治疗中度长度球部尿道狭窄的结果,并分析影响手术成功率的预测因素。
本研究共监测了 51 例平均长度为 4.4cm 的球部尿道狭窄患者,随访时间平均为 17 个月。从手术和术后数据中,我们评估了狭窄长度、手术时间、Qmax、国际前列腺症状评分、国际勃起功能指数-勃起功能和勃起后功能、总成功率和亚组成功率(年龄、根据 DVIU、病因、BMI 和 DM)、随访时间、并发症、再狭窄时间和数量。
手术的总成功率为 86.3%。在 17 个月的随访中,再狭窄率为 13.7%。口腔和尿道并发症均为轻微。持续时间最长(6 个月)的并发症是射精、勃起问题和尿道瘘。再狭窄的平均时间为 11 个月。所有再狭窄患者均通过单次 DVIU 治疗得到缓解。
对于长度超过 2cm 且有复发的球部尿道狭窄,背侧颊黏膜移植物替代是一种非常成功的方法,并发症发生率低。