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采用颊黏膜移植尿道成形术修复球部尿道狭窄。

Bulbar uretheral stricture repair with buccal mucosa graft urethroplasty.

作者信息

Ahmad Hussain, Mahmood Arshad, Niaz Waqar Azim, Akmal Muhammad, Murtaza Badar, Nadim Amir

机构信息

Department of Urology, Armed Forces Institute of Urology, Rawalpindi.

出版信息

J Pak Med Assoc. 2011 May;61(5):440-2.

Abstract

OBJECTIVE

To evaluate the use of buccal mucosa graft in single stage urethral reconstruction of bulbar urethral stricture.

METHODS

In Armed Forces Institute of Urology Rawalpindi, from Jan 2008 to Oct 2009, 56 patients underwent single stage dorsal onlay urethroplasty using buccal mucosa graft for long bulbar urethral strictures (> 2cm). Urethra was incised along the strictured segment in the 12 o'clock (dorsal) position starting from the distal end. A buccal mucosa graft of required length was harvested. The graft was anchored in a spread fixed fashion to the corporal bodies opposing the dorsally incised strictured urethra. The urethra was rotated back to the normal anatomic position. The margins of urethral incision were sutured to the fixed graft edge and corporal body using interrupted 4-0 vicryl. After completion of right margin's stitches, a 16 Fr silicon catheter was placed and then left margin stitches were completed.

RESULTS

Only 54 out of 56 patients could be evaluated because 2 patients were lost to follow up. Mean age of the patients was 48 +/- 11.32 years (range 19-67 yrs). Mean length of the buccal mucosa graft was 3.4 +/- 0.6 cm (range 2.6 - 5.5 cm). Duration of follow up was 4-20 months, mean 16.3 +/- 3.65 months. In 47 (87%) patients, the procedure was successful, 7 (13%) patients developed recurrence, out of these 7 patients, 2 (3.7%) required optical urethrotomy and 5 (9.25%) patients responded to urethral dilatation. Mean operative time was 92 +/- 13.22 minutes.

CONCLUSION

Buccal mucosa graft urethroplasty produces encouraging results in long bulbar urethral strictures. Longer follow up is required.

摘要

目的

评估颊黏膜移植片在球部尿道狭窄一期尿道重建中的应用。

方法

在拉瓦尔品第武装部队泌尿外科研究所,2008年1月至2009年10月,56例患者因长段球部尿道狭窄(>2cm)接受了使用颊黏膜移植片的一期背侧镶嵌式尿道成形术。从远端开始,在12点(背侧)位置沿狭窄段切开尿道。切取所需长度的颊黏膜移植片。将移植片以展开固定的方式固定于与背侧切开的狭窄尿道相对的阴茎海绵体上。将尿道旋转回正常解剖位置。用4-0可吸收缝线间断缝合尿道切口边缘与固定的移植片边缘及阴茎海绵体。完成右侧边缘缝合后,置入一根16F硅胶导管,然后完成左侧边缘缝合。

结果

56例患者中仅54例可进行评估,因为2例患者失访。患者的平均年龄为48±11.32岁(范围19 - 67岁)。颊黏膜移植片的平均长度为3.4±0.6cm(范围2.6 - 5.5cm)。随访时间为4 - 20个月,平均16.3±3.65个月。47例(87%)患者手术成功,7例(13%)患者复发,在这7例患者中,2例(3.7%)需要直视下尿道切开术,5例(9.25%)患者经尿道扩张有效。平均手术时间为92±13.22分钟。

结论

颊黏膜移植片尿道成形术在长段球部尿道狭窄中取得了令人鼓舞的结果。需要更长时间的随访。

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