Elaev N R, Evdokimov L D, Ryzhakov A V
Biokhimiia. 1986 Apr;51(4):649-54.
It was shown that rat blood plasma contains two enzymes that inactivate alkaloids by transforming them into N-oxides. Both enzymes are hemoproteins: one of them consists of three different polypeptides with Mr of 63, 35 and 12 kD, while the other one is a single polypeptide with Mr of 73 kD. Both enzymes exhibit cooperative properties.
结果表明,大鼠血浆中含有两种酶,它们通过将生物碱转化为N-氧化物来使其失活。这两种酶都是血红蛋白:其中一种由三种不同的多肽组成,分子量分别为63、35和12 kD,而另一种是单一多肽,分子量为73 kD。这两种酶都表现出协同特性。