[胰腺脱氧核糖核酸酶对热带假丝酵母核DNA拓扑结构的影响]
[Effect of pancreatic DNAse on the nuclear DNA topology of Candida tropicalis yeasts].
作者信息
Kupriianova F G, Davydova M N, Kuznetsova N N, Vinter V G
出版信息
Nauchnye Doki Vyss Shkoly Biol Nauki. 1986(4):24-9.
PMID:3708027
Abstract
It has been shown that pancreatic DNAase added to the nutritious medium caused the change in the nuclear DNA topology of asporogenic Candida tropicalis yeast. DNA conformative changes are due to the unwinding of supertwisted molecules as a result of single-strand ruptures formation which induce DNA synthesis acceleration, cell growth and division.
摘要
已经表明，添加到营养培养基中的胰腺脱氧核糖核酸酶会导致产孢热带假丝酵母酵母的核DNA拓扑结构发生变化。DNA构象变化是由于超螺旋分子解旋，这是由于单链断裂的形成导致的，单链断裂会加速DNA合成、细胞生长和分裂。
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