2000 年至 2021 年体外冲击波疗法（ESWT）研究的全球趋势。

BACKGROUND: This study intended to analyze the application of extracorporeal shock wave therapy in medicine and to evaluate the quality of related literature. METHODS: All publications were extracted from 2000 to 2021 from the Web of Science Core Collection (WoSCC). The literature characteristics were depicted by VOSviewer (version 1.6.15) and the online bibliometric website ( http://bibliometric.com/ ). The future trends and hotspots were conducted by Bibliographic Item Co-occurrence Matrix Builder (version 2.0) and gCLUTO software. RESULTS: We analyzed 1774 articles corresponding to the criteria for ESWT publications from 2000 to 2021. Most studies were conducted within the United States and China which besides have the most cooperation. The most published research institutions are Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, and Kaohsiung Medical University. Six research hotspots were identified by keyword clustering analysis: Cluster0: The effects of ESWT on muscle spasticity; Cluster1: The application of ESWT in osteoarthritis (OA); Cluster2: Therapeutic effect of ESWT on tendon diseases; Cluster3: Early application of ESWT/ESWL in urolithiasis; Cluster4: The Role of angiogenesis in ESWT and the efficiency of ESWT for penile disease; Cluster5: The Special value of radial extracorporeal shock wave therapy (rESWT). CONCLUSIONS: A comprehensive and systematic bibliometric analysis of ESWT was conducted in our study. We identified six ESWT-related research hotspots and predicted future research trends. With the gradual increase of research on ESWT, we find that ESWT is used more and more extensively, such in musculoskeletal disease, bone delay union, neurological injury, andrology disorders, lymphedema, and so on. In addition, the mechanism is not destructive damage, as initially thought, but a restorative treatment. Furthermore, delayed union, cellulite, burn, and diabetic foot ulcers may be the future direction of scientific study.

背景：本研究旨在分析体外冲击波疗法在医学中的应用，并评估相关文献的质量。

方法：从 Web of Science 核心合集（WoSCC）中提取了 2000 年至 2021 年的所有出版物。使用 Vosviewer（版本 1.6.15）和在线文献计量网站（http://bibliometric.com/）描绘文献特征。使用 Bibliographic Item Co-occurrence Matrix Builder（版本 2.0）和 gCLUTO 软件进行未来趋势和热点分析。

结果：我们分析了 2000 年至 2021 年符合 ESWT 出版物标准的 1774 篇文章。大多数研究在美国和中国进行，这两个国家的合作也最多。发表论文最多的研究机构是长庚大学、高雄长庚纪念医院和高雄医学大学。通过关键词聚类分析确定了 6 个研究热点：Cluster0：ESWT 对肌肉痉挛的影响；Cluster1：ESWT 在骨关节炎（OA）中的应用；Cluster2：ESWT 对肌腱疾病的治疗效果；Cluster3：ESWT/ESWL 在尿路结石中的早期应用；Cluster4：血管生成在 ESWT 中的作用和 ESWT 对阴茎疾病的效率；Cluster5：径向体外冲击波疗法（rESWT）的特殊价值。

结论：本研究对 ESWT 进行了全面系统的文献计量分析。我们确定了 6 个与 ESWT 相关的研究热点，并预测了未来的研究趋势。随着对 ESWT 的研究逐渐增加，我们发现 ESWT 的应用越来越广泛，如在肌肉骨骼疾病、骨延迟愈合、神经损伤、男科疾病、淋巴水肿等方面。此外，其机制不是最初认为的破坏性损伤，而是一种修复性治疗。此外，延迟愈合、蜂窝织炎、烧伤和糖尿病足溃疡可能是未来科学研究的方向。