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[Glio-neuronal aggregates in collagen gel: a model for studying the factors affecting development of central nervous system cells].

作者信息

Viktorov I V, Shashkova N A

出版信息

Biull Eksp Biol Med. 1986 May;101(5):611-4.

PMID:3708149
Abstract

Glio-neuronal aggregates of dissociated cells obtained from embryonic brain during cultivation in rotating flasks were transfered for further cultivation into collagen gel, containing balanced salt solution, serum-free amino acid medium, or complete nutrient medium. Active neurite growth and glial cell migration were observed during cultivation in collagen gel. The experiments have shown that glio-neuronal aggregates may serve as an experimental model for testing the activity of different neuronotrophic and neurite growth stimulating factors.

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