Shahnaz Mahaboob, Shalini Nair, Shereefa Abdul Qayyum, Vikas Kuruvilla
Department of Oral Pathology, PSM College of Dental Sciences and Research, Akkikavu, Kerala, India.
Department of Oral Surgery, PSM College of Dental Sciences and Research, Akkikavu, Kerala, India.
J Oral Maxillofac Pathol. 2023 Feb;27(Suppl 1):S20-S23. doi: 10.4103/jomfp.jomfp_260_22. Epub 2023 Feb 4.
'Hibernoma' is a neoplasm that arises from vestiges of fetal brown fat, and its occurrence in oral cavity is extremely rare. Its most common locations include thighs, the inter-scapular region, and the cervical region. In the present case, a 37-year-old male patient reported to our department with a localized swelling on his lower left labial mucosa along with multiple cutaneous well-defined swellings on his right arm and abdominal region. Incisional biopsy was carried out. Histopathological examination revealed sheets of multi-vacuolated eosinophilic cells with the granular cytoplasm interspersed with fat cells suggestive of oral hibernoma. These are rare lesions and could be often a missed-out diagnosis. Therefore, it is imperative to consider oral hibernoma among the commonly considered differential diagnosis of oral mucosal swellings.
“冬眠瘤”是一种起源于胎儿棕色脂肪遗迹的肿瘤,其在口腔中的发生极为罕见。它最常见的部位包括大腿、肩胛间区域和颈部。在本病例中,一名37岁男性患者前来我科就诊,其左下唇黏膜有局限性肿胀,右臂和腹部有多个边界清晰的皮肤肿胀。进行了切开活检。组织病理学检查显示成片的多空泡嗜酸性细胞,其颗粒状细胞质中散布着脂肪细胞,提示为口腔冬眠瘤。这些是罕见病变,常常可能漏诊。因此,在口腔黏膜肿胀的常见鉴别诊断中必须考虑口腔冬眠瘤。