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袋鼠式护理联合新生儿光疗对非病理性黄疸新生儿的疗效:一项荟萃分析。

Efficacy of kangaroo mother care combined with neonatal phototherapy in newborns with non-pathological jaundice: A meta-analysis.

作者信息

Huang Xiang, Chen Meiling, Fu Rongrong, He Wei, He Yujing, Shentu Haojie, Zhu Suping

机构信息

Department of Pediatric, Ningbo Yinzhou No. 2 Hospital, Ningbo, China.

The Public Health College, Zhejiang Chinese Medical University, Hangzhou, China.

出版信息

Front Pediatr. 2023 Jan 25;11:1098143. doi: 10.3389/fped.2023.1098143. eCollection 2023.

Abstract

BACKGROUND

The kangaroo-mother care method (KMC) is a skin-to-skin contact-centered care approach with numerous benefits for neonates, but its impact on the treatment of jaundiced neonates is unknown. This study aimed to investigate the efficacy of KMC combined with neonatal phototherapy (NNPT) in treating neonates with non-pathological jaundice.

METHODS

Relevant articles were searched in PubMed, Embase, Web of Science, and Cochrane Library databases from database establishment to April 2022. The outcomes included, without limitation, serum bilirubin levels, and duration of phototherapy.

RESULTS

This meta-analysis included five studies (4 randomized controlled trials and 1 observational study) involving four hundred eighty-two neonates with non-pathological jaundice. The results showed that the group receiving KMC combined with NNPT had lower serum bilirubin at 72 h after intervention [weighted mean difference (WMD) = -1.51,  = 0.03], shorter duration of phototherapy [standard mean difference (SMD) = -1.45,  < 0.001] and shorter duration of hospitalization (SMD = -1.32,  = 0.002) compared to NNPT group. There was no difference in peak bilirubin in both groups of neonates (WMD = -0.12,  = 0.62).

CONCLUSIONS

KMC combined with NNPT helped to treat non-pathological jaundice in newborns compared to NNPT alone.

摘要

背景

袋鼠式护理法(KMC)是以皮肤接触为核心的护理方法,对新生儿有诸多益处,但其对新生儿黄疸治疗的影响尚不清楚。本研究旨在探讨KMC联合新生儿光疗(NNPT)治疗非病理性黄疸新生儿的疗效。

方法

从数据库建立至2022年4月,在PubMed、Embase、Web of Science和Cochrane Library数据库中检索相关文章。结果包括但不限于血清胆红素水平和光疗持续时间。

结果

本荟萃分析纳入了五项研究(4项随机对照试验和1项观察性研究),涉及482例非病理性黄疸新生儿。结果显示,与NNPT组相比,接受KMC联合NNPT的组在干预后72小时血清胆红素水平更低[加权平均差(WMD)=-1.51,P=0.03],光疗持续时间更短[标准化平均差(SMD)=-1.45,P<0.001],住院时间更短(SMD=-1.32,P=0.002)。两组新生儿的胆红素峰值无差异(WMD=-0.12,P=0.62)。

结论

与单独使用NNPT相比,KMC联合NNPT有助于治疗新生儿非病理性黄疸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9d8/10112003/7c2d1bbf43d9/fped-11-1098143-g001.jpg

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