• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Successful Treatment of Paediatric Morphea with Tofacitinib.

作者信息

Tang Jun-Chi, Zheng Wen-Yue, Han Guang-Ming, Liu Shuang-Fei, Yang Bin

机构信息

Department of Dermatology, Guangdong College of Clinical Dermatology, Anhui Medical University, Guangzhou, China.

2Department of Dermatology and Rheumatology, Dermatology Hospital of Southern Medical University, Guangzhou, China.

出版信息

Acta Derm Venereol. 2023 Apr 21;103:adv4805. doi: 10.2340/actadv.v103.4805.

DOI:10.2340/actadv.v103.4805
PMID:37083093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10134061/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d23/10134061/2b5065868e81/ActaDV-103-4805-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d23/10134061/fb0a7fb4571c/ActaDV-103-4805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d23/10134061/2b5065868e81/ActaDV-103-4805-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d23/10134061/fb0a7fb4571c/ActaDV-103-4805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d23/10134061/2b5065868e81/ActaDV-103-4805-g002.jpg

相似文献

1
Successful Treatment of Paediatric Morphea with Tofacitinib.托法替布成功治疗儿童硬斑病
Acta Derm Venereol. 2023 Apr 21;103:adv4805. doi: 10.2340/actadv.v103.4805.
2
Successful therapy of refractory cutaneous morphea with tofacitinib.托法替布成功治疗难治性皮肤硬斑病
Ital J Dermatol Venerol. 2024 Aug;159(4):469-470. doi: 10.23736/S2784-8671.24.07925-8. Epub 2024 May 23.
3
Effect of the Janus kinase inhibitor tofacitinib in the treatment of juvenile scleroderma: A single-center experience.Janus激酶抑制剂托法替布治疗青少年硬皮病的疗效:单中心经验
Int J Rheum Dis. 2024 Aug;27(8):e15295. doi: 10.1111/1756-185X.15295.
4
Full histological and clinical regression of morphea with tofacitinib.托法替布治疗硬斑病实现完全组织学和临床缓解。
Clin Rheumatol. 2020 Sep;39(9):2827-2828. doi: 10.1007/s10067-020-05118-z. Epub 2020 May 18.
5
Successful combination treatment of a patient with progressive juvenile localized scleroderma (morphea) using imatinib, corticosteroids, and methotrexate.使用伊马替尼、皮质类固醇和甲氨蝶呤成功联合治疗一名进行性青少年局限性硬皮病(硬斑病)患者。
Pediatr Dermatol. 2013 Nov-Dec;30(6):e191-3. doi: 10.1111/j.1525-1470.2012.01882.x. Epub 2012 Oct 2.
6
Imatinib treatment of generalized localized scleroderma (morphea).伊马替尼治疗泛发性局限性硬皮病(硬斑病)。
J Am Acad Dermatol. 2010 Nov;63(5):e102-4. doi: 10.1016/j.jaad.2010.02.030.
7
Morphea and other localized forms of scleroderma.硬皮病的硬斑病和其他局限性形式。
Curr Opin Rheumatol. 2012 Nov;24(6):685-93. doi: 10.1097/BOR.0b013e32835896ce.
8
[Linear morphea].[线状硬皮病]
Ned Tijdschr Geneeskd. 1998 Jul 4;142(27):1582-3.
9
Bullous lichen sclerosus-generalized morphea overlap syndrome improved by tofacitinib.类天疱疮样硬皮病-泛发性硬斑病重叠综合征经托法替尼治疗改善。
Dermatol Ther. 2022 Dec;35(12):e15942. doi: 10.1111/dth.15942. Epub 2022 Nov 3.
10
Progressive linear scleroderma and morphea in a child.一名儿童的进行性线状硬皮病和局限性硬皮病
J Pediatr. 1998 Aug;133(2):308. doi: 10.1016/s0022-3476(98)70244-6.

引用本文的文献

1
Janus kinase inhibitors in localized scleroderma: a systematic literature review.局部性硬皮病中的Janus激酶抑制剂:一项系统文献综述
Turk J Med Sci. 2025 Jun 7;55(3):533-539. doi: 10.55730/1300-0144.6000. eCollection 2025.
2
New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review.青少年硬皮病的新型挑战性全身治疗方法:综述
Pharmaceuticals (Basel). 2025 Apr 28;18(5):643. doi: 10.3390/ph18050643.
3
Emerging therapeutic targets in systemic sclerosis.系统性硬化症的新兴治疗靶点。

本文引用的文献

1
Janus kinase inhibitors for treatment of morphea and systemic sclerosis: A literature review.Janus 激酶抑制剂治疗硬斑病和系统性硬化症:文献复习。
Dermatol Ther. 2022 Jun;35(6):e15437. doi: 10.1111/dth.15437. Epub 2022 Mar 22.
2
Molecular and Histological Evidence Detailing Clinically Observed Skin Improvement Following Cryolipolysis.详细描述临床观察到的冷冻减脂治疗后皮肤改善的分子和组织学证据。
Aesthet Surg J. 2022 Jan 1;42(1):56-67. doi: 10.1093/asj/sjab226.
3
Exploring the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Glycyrrhizic and Glycyrrhetinic Acids.
J Mol Med (Berl). 2024 Apr;102(4):465-478. doi: 10.1007/s00109-024-02424-w. Epub 2024 Feb 22.
探讨甘草酸和甘草次酸的关键免疫调节和抗炎潜力。
Mediators Inflamm. 2021 Jan 7;2021:6699560. doi: 10.1155/2021/6699560. eCollection 2021.
4
JAK Inhibitors: Prospects in Connective Tissue Diseases.JAK 抑制剂:在结缔组织疾病中的前景。
Clin Rev Allergy Immunol. 2020 Dec;59(3):334-351. doi: 10.1007/s12016-020-08786-6.
5
Jak Inhibition Prevents Bleomycin-Induced Fibrosis in Mice and Is Effective in Patients with Morphea.Jak抑制可预防博来霉素诱导的小鼠纤维化,对硬斑病患者有效。
J Invest Dermatol. 2020 Jul;140(7):1446-1449.e4. doi: 10.1016/j.jid.2019.12.019. Epub 2020 Jan 16.
6
Interventions for morphea.硬斑病的干预措施。
Cochrane Database Syst Rev. 2019 Jul 16;7(7):CD005027. doi: 10.1002/14651858.CD005027.pub5.
7
Treatment of morphea with hydroxychloroquine: A retrospective review of 84 patients at Mayo Clinic, 1996-2013.羟氯喹治疗硬斑病:梅奥诊所 1996-2013 年 84 例回顾性研究。
J Am Acad Dermatol. 2019 Jun;80(6):1658-1663. doi: 10.1016/j.jaad.2019.01.040. Epub 2019 Jan 29.
8
PD-1 up-regulation on CD4 T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.PD-1 在 CD4 T 细胞上的上调通过 STAT3 介导的 IL-17A 和 TGF-β1 产生促进肺纤维化。
Sci Transl Med. 2018 Sep 26;10(460). doi: 10.1126/scitranslmed.aar8356.
9
Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.STAT3 的激活整合了常见的促纤维化途径,以促进成纤维细胞的激活和组织纤维化。
Nat Commun. 2017 Oct 24;8(1):1130. doi: 10.1038/s41467-017-01236-6.
10
The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells.JAK-STAT信号通路及其调节因子在辅助性T细胞命运中的作用。
Cell Commun Signal. 2017 Jun 21;15(1):23. doi: 10.1186/s12964-017-0177-y.