Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
J Vet Intern Med. 2023 May-Jun;37(3):1271-1277. doi: 10.1111/jvim.16704. Epub 2023 Apr 21.
There exists a scarcity of information on risk factors associated with case outcomes in goats diagnosed with encephalitic listeriosis.
Evaluate risk factors associated with outcomes in 36 cases of suspected encephalitic listeriosis in goats presented to a referral hospital.
Thirty-six goats (26 does, 7 bucks, and 3 wethers) were presented to Auburn University Large Animal Teaching Hospital between 2008 and 2021 for treatment of neurologic disease diagnosed as encephalitic listeriosis based on any combination of clinical signs, cerebral spinal fluid (CSF) analysis, or postmortem examination.
Retrospective study. Data were analyzed as binary and under a proportional odds model. The medical records were searched for presumptive encephalitic listeriosis in goats between 2008 and 2021. Data collected included signalment (sex, age, and breed), history, clinical signs, temperature, and ability to stand at presentation. Final diagnosis, CSF results, all treatments, outcomes, and results of necropsy were also collected for analysis.
Male goats were 14 (95% CI: 1.98-166.0) times more likely to be a non-survivor compared to females despite being presented with similar history, clinical signs, and treatments. Animals presented with circling or a history of circling were 6.24 (95% CI: 1.40-23.21) times more likely to be a survivor than a non-survivor. Other risk factors evaluated were not significantly associated with outcomes.
Few risk factors were associated with outcomes. Duration of clinical signs, antimicrobial or anti-inflammatory choices, or CSF results were not associated with outcome. Only sex and history or presence of circling were associated with case outcomes.
目前针对诊断为脑炎李斯特菌病的山羊病例结局相关的风险因素的信息有限。
评估在转诊医院就诊的 36 例疑似脑炎李斯特菌病山羊病例结局相关的风险因素。
2008 年至 2021 年，共有 36 只山羊（26 只母羊、7 只公羊和 3 只阉羊）因诊断为脑炎李斯特菌病的神经疾病而被送到奥本大学大型动物教学医院就诊，这些疾病的诊断依据是任何组合的临床症状、脑脊髓液（CSF）分析或剖检结果。
回顾性研究。数据以二进制形式和比例优势模型进行分析。在 2008 年至 2021 年期间，对山羊疑似脑炎李斯特菌病的病例进行了病历检索。收集的信息包括：一般情况（性别、年龄和品种）、病史、临床症状、体温和就诊时的站立能力。还收集了最终诊断、CSF 结果、所有治疗方法、结局以及剖检结果用于分析。
与雌性山羊相比，雄性山羊尽管具有相似的病史、临床症状和治疗方法，但更有可能成为非幸存者，其非幸存者的可能性是雌性山羊的 14 倍（95%CI：1.98-166.0）。出现转圈或有转圈病史的动物更有可能成为幸存者，而非非幸存者，其幸存的可能性是死亡的 6.24 倍（95%CI：1.40-23.21）。评估的其他风险因素与结局无显著相关性。
少数风险因素与结局相关。临床症状持续时间、抗菌或抗炎药物选择或 CSF 结果与结局无关。只有性别和转圈病史或出现转圈与病例结局相关。
