Hallak Bassel, Teiga Pedro, Hedjoudje Abderrahmane, Alvarez Vincent
Department of Otorhinolaryngology, Head and Neck Surgery, Sion Hospital, Sion, Switzerland
Department of Otorhinolaryngology, Head and Neck Surgery, Sion Hospital, Sion, Switzerland.
BMJ Case Rep. 2023 Apr 21;16(4):e253788. doi: 10.1136/bcr-2022-253788.
Invasive fungal sinusitis (IFS) is more common in immunosuppressed patients but can also occur in immunocompetent hosts. While the non-invasive type of fungal sinusitis has usually a good prognosis, IFS is a potentially lethal condition.We report the case of a woman in her 60s presenting an isolated fungal infection by of the right sphenoid sinus, causing extensive bone erosion of its walls and complicated by severe meningoencephalitis. She was healthy without any immunosuppressive conditions. Methods of diagnosis, multidisciplinary management, follow-up and outcomes are documented.Early-stage diagnosis of sphenoid sinus pathologies is often delayed because patients are usually asymptomatic. IFS of the sphenoid is more aggressive than other paranasal sinus and carries significant mortality. Early diagnosis and aggressive and multidisciplinary treatment are crucial to reduce sequels and improve patient's survival.
侵袭性真菌性鼻窦炎（IFS）在免疫抑制患者中更为常见，但也可发生于免疫功能正常的宿主。虽然非侵袭性真菌性鼻窦炎通常预后良好，但IFS是一种潜在的致命疾病。我们报告了一例60多岁女性的病例，该患者右侧蝶窦出现孤立性真菌感染，导致蝶窦壁广泛骨质侵蚀，并并发严重的脑膜脑炎。她身体健康，无任何免疫抑制状况。记录了诊断方法、多学科管理、随访及结果。蝶窦病变的早期诊断往往延迟，因为患者通常无症状。蝶窦IFS比其他鼻窦更具侵袭性，且死亡率较高。早期诊断以及积极的多学科治疗对于减少后遗症和提高患者生存率至关重要。
