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COVID-19 大流行期间髋部骨折手术患者的发病率和死亡率。

Morbidity and mortality in hip surgery patients due to fracture during the COVID-19 pandemic.

机构信息

Hip and Orthopedic Trauma Surgeon, Clínica Universitaria Colombia, Bogotá, Colombia.

Hip and Orthopedic Trauma Surgeon, Los Cobos Medical Center, Bogotá, Colombia.

出版信息

Injury. 2023 Nov;54 Suppl 6:110731. doi: 10.1016/j.injury.2023.04.018. Epub 2023 Apr 15.

Abstract

BACKGROUND

The COVID-19 epidemic generated major changes in general surgical management protocols. The literature has reported high mortality rates for hip fracture surgery in patients with COVID-19. This study describes the morbidity and mortality in patients undergoing surgery due to hip fractures in 12 Colombian institutions between March and September 2020.

METHODOLOGY

This was a retrospective observational descriptive study. Medical records of 12 hospitals were reviewed. Consecutive patients who underwent hip fracture surgery from March 6 to September 6, 2020, were included. Data collected were sociodemographic profile, type of fracture, surgical treatment, complications, and early (1 month) or mid-term (1-6 months) mortality associated or not with COVID-19.

RESULTS

Five hundred twenty patients with hip fractures requiring surgery in the 12 institutions were included. 364 (70%) were women; mean age was 77.7 years (SD: 13.8), mean BMI was 25.1, 91.73% of patients had at least one comorbidity, 60.38% were classified as ASA II and 25.77% as ASA III. There were 267 (51.34%) pertrochanteric fractures, 227 (43.65%) femoral neck fractures, and 26 (5.0%) subtrochanteric fractures. 274 (52.69%) patients were treated with osteosynthesis, 244 (46.92%) with arthroplasty, and 2 (0.38%) with girdlestone. Surgery was performed less than 24 h after the fracture for 115 (22.11%) patients, between 24 and 72 h for 208 (40.0%) patients, and more than 72 h for 197 (37.88%) patients. One hundred six patients in total suffered a medical or surgical complication throughout the different follow-up stages, amongst the most frequent were respiratory failure, coronary events, surgical site infection, cutting-out and peri‑implant fracture. 25 (4.8%) patients required attention in the Intensive Care Unit (ICU). 13 patients had COVID-19 throughout the follow-up period. 27 patients died due to any cause, and 3 of them had reported a positive COVID-19 test any time during follow-up period, of which one died during the first month, and two died between 1 and 6 months. Statistically significant associations were found between age older than 75 years old, ASA classification, ICU requirement, and death.

CONCLUSION

520 patients received surgical treatment for hip fracture during the first six months of the COVID-19 pandemic in 12 medical centers in Colombia. 21.10% suffered a complication during the early stage (30 days) and 4.77% during the midterm stage (1-6 months). 4.8% were admitted in the ICU during the early stage. All-cause death was 27 patients, early death was 11 (40.74%) and midterm death was 16 (59.25%). 13 patients were positive for COVID-19, 3 died, one (1/5=20%) on the first 30 days and the other two (2/8=25%) from month 1 to 6.

摘要

背景

COVID-19 疫情对普通外科管理方案产生了重大变化。文献报道 COVID-19 患者髋部骨折手术的死亡率较高。本研究描述了 2020 年 3 月至 9 月期间 12 家哥伦比亚机构因髋部骨折接受手术的患者的发病率和死亡率。

方法

这是一项回顾性观察描述性研究。对 12 家医院的病历进行了回顾。纳入了 2020 年 3 月 6 日至 9 月 6 日期间因髋部骨折接受手术的连续患者。收集的数据包括社会人口统计学特征、骨折类型、手术治疗、并发症以及与 COVID-19 相关或不相关的早期(1 个月)或中期(1-6 个月)死亡率。

结果

在 12 家机构中有 520 名需要手术治疗的髋部骨折患者被纳入研究。364 名(70%)为女性;平均年龄为 77.7 岁(标准差:13.8),平均 BMI 为 25.1,91.73%的患者至少有一种合并症,60.38%的患者为 ASA II 级,25.77%为 ASA III 级。有 267 名(51.34%)为股骨转子间骨折,227 名(43.65%)为股骨颈骨折,26 名(5.0%)为转子下骨折。274 名(52.69%)患者接受骨接合术治疗,244 名(46.92%)接受关节置换术治疗,2 名(0.38%)接受股骨切除术。115 名(22.11%)患者在骨折后 24 小时内进行手术,208 名(40.0%)患者在 24-72 小时内进行手术,197 名(37.88%)患者在 72 小时后进行手术。106 名患者在不同的随访阶段出现了医疗或手术并发症,其中最常见的是呼吸衰竭、冠状动脉事件、手术部位感染、钢板脱出和植入物周围骨折。25 名(4.8%)患者需要在重症监护病房(ICU)接受治疗。13 名患者在整个随访期间患有 COVID-19。27 名患者因任何原因死亡,其中 3 名患者在随访期间任何时候均报告 COVID-19 检测呈阳性,其中 1 名在第一个月死亡,2 名在 1-6 个月期间死亡。年龄大于 75 岁、ASA 分级、需要 ICU 治疗与死亡之间存在统计学显著相关性。

结论

在哥伦比亚 12 家医疗中心,520 名患者在 COVID-19 大流行的头 6 个月内接受了髋部骨折手术治疗。早期(30 天)有 21.10%的患者发生并发症,中期(1-6 个月)有 4.77%的患者发生并发症。早期有 4.8%的患者需要入住 ICU。所有原因的死亡为 27 例,早期死亡为 11 例(40.74%),中期死亡为 16 例(59.25%)。13 名患者 COVID-19 检测呈阳性,3 名死亡,其中 1 名(1/5=20%)在第 30 天内死亡,另外 2 名(2/8=25%)在第 1-6 个月内死亡。

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