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猴痘感染患者的直肠炎:来自一项多学科猴痘直肠炎观察性研究的 42 例连续病例的单中心分析。

Proctitis in patients with monkeypox infection: a single-center analysis of 42 consecutive cases from a multidisciplinary observational study on monkeypox proctitis.

机构信息

General and Digestive Surgery, Hospital Universitario La Paz. Universidad Autónoma de Madrid, Madrid, Spain.

Instituto de Investigación, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Tech Coloproctol. 2023 Dec;27(12):1211-1218. doi: 10.1007/s10151-023-02782-6. Epub 2023 Apr 22.

Abstract

BACKGROUND

The current monkeypox (MP) virus outbreak was declared an international emergency in July 2022. The aim of this report is to describe our initial experience with patients with MP, focusing on proctitis.

METHODS

We conducted an observational study between 20 May and 31 July 2022, on patients with MP at a reference tertiary center in Madrid, Spain. A descriptive analysis on MP was performed, focusing on its characteristics, symptoms, diagnosis, and outcomes.

RESULTS

A total of 143 positive MP cases were diagnosed in our center; 42 of them [all male, median age 39 years (range: 22-57 years)] had proctitis (29.37%), and 3 patients (2.09%/MP total cases and 7.14%/MP proctitis) required surgical drainage of a perianal abscess.

CONCLUSIONS

General and digestive surgeons must be aware of the presence of proctological impairment and complications due to MP virus.

摘要

背景

当前的猴痘(MP)病毒疫情于 2022 年 7 月被宣布为国际紧急事件。本报告的目的是描述我们在猴痘患者方面的初步经验,重点是直肠炎。

方法

我们在西班牙马德里的一家参考三甲中心进行了一项观察性研究,时间为 2022 年 5 月 20 日至 7 月 31 日,研究对象为猴痘患者。对 MP 进行了描述性分析,重点是其特征、症状、诊断和结果。

结果

我们中心共诊断出 143 例阳性猴痘病例;其中 42 例(均为男性,中位年龄 39 岁(范围:22-57 岁))患有直肠炎(29.37%),3 例患者(2.09%/MP 总病例和 7.14%/MP 直肠炎)需要肛周脓肿切开引流。

结论

普通和消化外科医生必须意识到猴痘病毒引起的直肠功能障碍和并发症的存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2668/10638120/f4f4b285bfbf/10151_2023_2782_Fig1_HTML.jpg

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