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一名年轻男性前列腺胚胎性横纹肌肉瘤:罕见病例报告。

Embryonal rhabdomyosarcoma of the prostate in a young male: A rare case report.

作者信息

Alenezi Saad, Zahir Mohammed, Alenezi Jarah

机构信息

Urology department, Jaber Alahmad Hospital, Kuwait; University of Jordan, Amman, Jordan.

Urology department, Al Jahra Hospital, Kuwait.

出版信息

Int J Surg Case Rep. 2023 May;106:108228. doi: 10.1016/j.ijscr.2023.108228. Epub 2023 Apr 18.

Abstract

INTRODUCTION AND IMPORTANCE

Embryonal rhabdomyosarcoma (ERMS) of the prostate is a rare disease, and it has a poor prognosis. Mostly patient come with late stage thus with delayed diagnosis and worse outcomes.

CASE PRESENTATION

a 35-year-old Bangladeshi male presented with bladder outlet obstruction in an intermittent pattern. Patient was not complaining from any other urological symptoms, there was no hematuria or dysuria, even no constitutional symptoms, no history of weight loss, no anorexia or night rigors, also there was no history of fever. Patients have an only previous history of spinal screw without any other medical illnesses. Patient came to casualty with frequent visits without any inflammatory markers elevation even with normal biochemical labs. O/E he found to have a prostatic mass on PR examination of which patient admitted to urology department and underwent diagnostic cystoscopy which showed cauliflower mass at the prostatic urethra. Biopsies retrieved and showed embryonal rhabdomyosarcoma (RMS) of the prostate under the histopathological examination.

CLINICAL DISCUSSION

Embryonal rhabdomyosarcoma (ERMS) mostly care a poor prognosis and modalities vary according to the presentation and the stage. However distant metastasis is common at the time of presentation.

CONCLUSION

embryonal rhabdomyosarcoma of the prostate is a rare and aggressive tumor with a low survival rate in adults. However, more clinical data needed for a better outcome.

摘要

引言与重要性

前列腺胚胎性横纹肌肉瘤(ERMS)是一种罕见疾病,预后较差。大多数患者就诊时已处于晚期,因此诊断延迟且预后更差。

病例介绍

一名35岁的孟加拉男性间歇性出现膀胱出口梗阻。患者无其他泌尿系统症状,无血尿或尿痛,甚至无全身症状,无体重减轻史,无厌食或夜间寒战,也无发热史。患者既往仅有脊柱螺钉置入史,无其他疾病史。患者频繁前往急诊,炎症指标未升高,生化检查结果正常。经直肠检查发现前列腺有肿块,患者被收入泌尿外科,接受了诊断性膀胱镜检查,结果显示前列腺尿道有菜花样肿块。活检组织经组织病理学检查显示为前列腺胚胎性横纹肌肉瘤(RMS)。

临床讨论

胚胎性横纹肌肉瘤(ERMS)大多预后不良,治疗方式因临床表现和分期而异。然而,就诊时远处转移很常见。

结论

前列腺胚胎性横纹肌肉瘤是一种罕见且侵袭性强的肿瘤,成人患者生存率低。然而,需要更多临床数据以获得更好的治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e95/10154731/5399ce7e1fb3/gr1.jpg

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