Faculty of Engineering, Department of Mechanical Engineering, Institut Teknologi Padang, Kp Olo, 25143, Padang, Sumatera Barat, Indonesia.
Faculty of Engineering, Department of Mechanical Engineering, Institut Teknologi Padang, Kp Olo, 25143, Padang, Sumatera Barat, Indonesia.
J Mech Behav Biomed Mater. 2023 Jun;142:105862. doi: 10.1016/j.jmbbm.2023.105862. Epub 2023 Apr 17.
Poly(methyl methacrylate) (PMMA)-based scaffolds have been produced using the granule casting method with grain sizes M80-100 and M100-140. The novelty of this study was the application of the cold-cutting method (CCm) to reduce the PMMA granule size. PMMA granule shape, granule size (mesh), and sintering temperature were the primary variables in manufacturing PMMA scaffolds. CCm was applied to reduce the granule size of commercial PMMA, which was originally solid cylindrical, by lowering the temperature to 3.5 °C, 0 °C, and-8.3 °C. PMMA granules that had been reduced were sieved with mesh sizes M80-100 and M100-140. Green bodies were made by the granule casting method using an aluminum mold measuring 8 × 8 × 8 mm. The sintering process was carried out at temperatures varying from 115 °C to 140 °C, a heating rate of 5 °C/min, and a holding time of 2 h, the cooling process was carried out in a furnace. The characterization of the PMMA-based scaffolds' properties was carried out by observing the microstructure with SEM, analyzing the distribution of pore sizes with ImageJ software, and testing the porosity, the phase, with XRD, and the compressive strength. The best results from the overall analysis were the M80-100 PMMA scaffold treated at a sintering temperature of 130 °C with compressive strength, porosity, and pore size distribution values of 8.2 MPa, 62.0%, and 121-399 μm, respectively, and the M100-140 one treated at a sintering temperature of 135 °C with compressive strength, porosity, and pore size distribution values of 12.1 MPa, 61.2%, and 140-366 μm, respectively. There were interconnected pores in the PMMA scaffolds, as evidenced by the SEM images. There was no PMMA phase change between before and after the sintering process.
采用粒度为 M80-100 和 M100-140 的造粒浇注法制备了聚甲基丙烯酸甲酯(PMMA)基支架。本研究的新颖之处在于采用冷切割法(CCm)来减小 PMMA 颗粒的尺寸。PMMA 颗粒形状、颗粒尺寸(目数)和烧结温度是制造 PMMA 支架的主要变量。CCm 用于降低商用 PMMA 颗粒的尺寸,原本为实心圆柱形,将温度降至 3.5°C、0°C 和-8.3°C。降低后的 PMMA 颗粒用 M80-100 和 M100-140 目数的筛子进行筛分。采用粒料浇注法,将粒径为 8×8×8mm 的铝模具制成生坯。烧结过程在 115°C 至 140°C 的温度下进行,升温速率为 5°C/min,保温时间为 2h,冷却过程在炉中进行。采用 SEM 观察微观结构、ImageJ 软件分析孔径分布、XRD 测试孔隙率、相结构和抗压强度等方法对 PMMA 基支架的性能进行了表征。从整体分析来看,最佳结果是在 130°C 下烧结的 M80-100 PMMA 支架,其抗压强度、孔隙率和孔径分布分别为 8.2MPa、62.0%和 121-399μm,以及在 135°C 下烧结的 M100-140 PMMA 支架,其抗压强度、孔隙率和孔径分布分别为 12.1MPa、61.2%和 140-366μm。SEM 图像表明,PMMA 支架中存在连通孔。烧结前后 PMMA 相没有变化。