Clinical Microbiology Service, Basurto University Hospital, 18 Avenida Montevideo, 48013, Bilbao, Biscay, Spain; Biocruces Bizkaia Health Research Institute, Cruces Plaza, 48903, Biscay, Spain.
Radiodiagnosis Service of Cruces University Hospital, Spain.
Anaerobe. 2023 Jun;81:102733. doi: 10.1016/j.anaerobe.2023.102733. Epub 2023 Apr 21.
The genus Fusobacterium contains currently 13 species presenting as non-sporing, obligate anaerobic, Gram-negative fusiform rods. Fusobacterium ulcerans was discovered in 1988 causing tropical ulcers. We present the case of a patient with diverticulitis complicated with bacteremia. Both aerobic bottles were positive at 20 and 24 h, while one anaerobic bottle was positive at 36 h. Escherichia coli and Fusobacterium ulcerans were identified from subcultures by MALDI-TOF MS with a score of 2.02 and 2.35, respectively. The 16S rRNA gene was sequenced in order to confirm the identification of F. ulcerans with a 100% homology to the reference strain. The patient was treated with 4 g/0,5 g of IV piperacillin/tazobactam and later with 1 g/0,2 g of amoxicillin/clavulanic during 7 days with good clinical evolution.
梭杆菌属目前包含 13 个种，呈现为非孢子形成、专性厌氧、革兰阴性梭形杆菌。1988 年发现了导致热带溃疡的梭杆菌溃疡亚种。我们报告了一例患有憩室炎并伴有菌血症的患者。需氧瓶在 20 和 24 小时时均为阳性，而一个厌氧瓶在 36 小时时为阳性。MALDI-TOF MS 从亚培养物中鉴定出大肠杆菌和梭杆菌溃疡亚种，其得分分别为 2.02 和 2.35。为了确认梭杆菌溃疡亚种的鉴定，对 16S rRNA 基因进行了测序，与参考株具有 100%的同源性。患者接受了 4 g/0.5 g 的 IV 哌拉西林/他唑巴坦，随后在 7 天内接受了 1 g/0.2 g 的阿莫西林/克拉维酸治疗，临床情况良好。
