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首例由梭菌引起的菌血症坏死性胆囊炎。

First case of bacteremia caused by Cetobacterium somerae following necrotizing cholecystitis.

机构信息

Department of Clinical Infectious Diseases, Kochi Medical School, Kochi University, Japan; Division of Infection and Prevention, Kochi Medical School Hospital, Japan.

Division of Infection and Prevention, Kochi Medical School Hospital, Japan; Department of Clinical Laboratory, Kochi Medical School Hospital, Japan.

出版信息

J Infect Chemother. 2023 Sep;29(9):905-908. doi: 10.1016/j.jiac.2023.05.005. Epub 2023 May 11.

DOI:10.1016/j.jiac.2023.05.005
PMID:37178976
Abstract

Cetobacterium somerae, a gram-negative anaerobic rod, first identified in the feces of children with autism, also colonize freshwater fish intestinal tract. However there have been no reports of human C. somerae infection. Here, we describe the first case of C. somerae bacteremia in a patient with necrotizing cholecystitis. A 72-year-old male presented to the emergency department with chills, vomiting, and fever and was diagnosed with acute necrotizing cholecystitis. An emergency cholecystectomy was performed and the following day, two sets of blood culture were positive for gram-negative bacilli. Identification of C. somerae from the biochemical profile was difficult but possible by mass spectrometry and 16s rRNA sequence.

摘要

西地西菌属梭菌,一种革兰氏阴性厌氧杆菌,最初在自闭症儿童的粪便中发现,也定植于淡水鱼类的肠道。然而,目前尚无人类感染西地西菌属梭菌的报道。在这里,我们描述了首例坏死性胆囊炎合并西地西菌属梭菌菌血症患者。一名 72 岁男性因寒战、呕吐和发热就诊于急诊科,被诊断为急性坏疽性胆囊炎。行急诊胆囊切除术,次日,两套血培养均为革兰氏阴性杆菌阳性。西地西菌属梭菌的生化特征鉴定困难,但通过质谱和 16s rRNA 序列鉴定是可行的。

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