Sección de Reumatología, Hospital Universitario de la Plana, Castellón, Spain.
Servicio de Reumatología, Hospital Universitario Dr. Peset, Valencia, Spain.
Reumatol Clin (Engl Ed). 2023 May;19(5):249-254. doi: 10.1016/j.reumae.2022.06.007. Epub 2023 Apr 20.
Psoriatic arthritis (PsA) is a chronic inflammatory disorder that primarily affects the joints and entheses. In addition, it is associated with depressive syndrome (DS), cardiovascular disease, hypertension (HT), diabetes mellitus (DM), obesity and psoriasis (Pso). There are few studies aimed to analyze the association of the involvement of the musculoskeletal system with sexual function (SF).
A cross-sectional observational study was proposed in patients diagnosed with PsA, to whom self-administered validated questionnaires were applied to determine alterations in SF: MGH-SFQ and CSFQ-14, which assess the 4 domains of sexual function; Qualisex and DLQI designed for joint and dermatological pathology respectively, which explore sexual aspects. The objective was to describe the existence of altered sexual function in patients with PsA; analyze the association between sociodemographic characteristics, comorbidities (Pso, DS, cardiovascular risk factors) and the treatments of patients on SF; and describe differences of SF according to gender.
72 patients were evaluated. It was observed that the variables of patients with PsA that were associated with lower scores in SF were gender and age in the CSFQ-14 and MGH-SFQ; annual incomes, treatment with NSAIDs, DL and depression were associated with worse results in some domains of the sexual sphere.
Patients with PsA had impaired SF, especially women, elder patiens, those with low annual incomes, DL and emotional disorders. Anti-inflammatory treatments were associated with better SF. Globally, the chronic disease and the psychological burden behaved as factors associated with sexual dysfunction.
银屑病关节炎(PsA)是一种慢性炎症性疾病,主要影响关节和附着点。此外,它与抑郁综合征(DS)、心血管疾病、高血压(HT)、糖尿病(DM)、肥胖和银屑病(Pso)有关。很少有研究旨在分析骨骼肌肉系统与性功能(SF)的关联。
在诊断为 PsA 的患者中提出了一项横断面观察性研究,对患者进行了自我管理的验证问卷,以确定 SF 的变化:MGH-SFQ 和 CSFQ-14,评估性功能的 4 个领域;Qualisex 和 DLQI 分别用于关节和皮肤病学病理学,探索性方面。目的是描述 PsA 患者性功能障碍的存在;分析社会人口统计学特征、合并症(Pso、DS、心血管危险因素)与患者 SF 治疗之间的关系;并根据性别描述 SF 的差异。
共评估了 72 名患者。观察到与 SF 评分较低相关的 PsA 患者变量是 CSFQ-14 和 MGH-SFQ 中的性别和年龄;年收入、NSAIDs、DL 和抑郁治疗与性领域某些领域的结果较差相关。
患有 PsA 的患者存在性功能障碍,尤其是女性、老年患者、年收入较低、DL 和情绪障碍患者。抗炎治疗与更好的 SF 相关。总体而言,慢性疾病和心理负担是与性功能障碍相关的因素。