Lobo Jokasta Nunes, Ramos Lysiane Maria Adeodato, Mont'Alverne Andrea Rocha de Saboia, de Carvalho Jozélio Freire, Rodrigues Carlos Ewerton Maia
Department of Rheumatology, Hospital Geral de Fortaleza, Ceará, Brazil.
Núcleo de Pesquisa em Doenças Crônicas não Transmissíveis (NUPEN), School of Nutrition from the Federal University of Bahia, Salvador, Bahia, Brazil.
North Clin Istanb. 2024 Jun 25;11(3):191-200. doi: 10.14744/nci.2023.75317. eCollection 2024.
Psoriatic arthritis (PsA) is a chronic inflammatory disorder affecting the joints, skin and entheses. Despite the importance of the topic, few studies have investigated the association between PsA and sexual function. The purpose of this study was to assess sexuality and the prevalence of sexual dysfunction (SD) in patients with PsA.
This was an observational, cross-sectional single-center study on 23 PsA patients (male=12; female=11) evaluated with 2 male questionnaires (MSQ= Male Sexual Quotient, and IIEF=International Index of Erectile Function) and 2 female questionnaires (FSQ= Female Sexual Quotient, and FSFI=Female Sexual Function Index) validated for Brazilian Portuguese, in order to determine changes in sexual function. Clinical parameters, musculoskeletal activity and skin activity were also analyzed to identify factors associated with SD.
The mean age was 52.1±9.7 years (males) and 49.1±9.6 years (females). Clinically, the patients had low skin and peripheral joint disease activity or were in remission. The mean time of PsA was 10±6.2 years, and 65.2% had a steady sexual partner. The mean MSQ score was 75.8±16.8. The prevalence of SD was 91.7% in men (IIEF), with a predominance of mild SD. The mean FSQ score was 64.9±24.1. The prevalence of SD was 72.7% in women (FSFI), with low domain scores. Also, a significant association was found between female age and total and domain-specific FSFI scores. PASI (Psoriasis Area and Severity Index) and the general satisfaction domain (IIEF) were significantly correlated.
This study found a high prevalence of SD in PsA patients. Age had a negative impact on female sexual function. Physicians need to be more aware of SD in this population to provide early multidisciplinary treatment and minimize the impact of the disease on the quality of life of patients and their partners.
银屑病关节炎（PsA）是一种影响关节、皮肤和附着点的慢性炎症性疾病。尽管该话题很重要，但很少有研究调查PsA与性功能之间的关联。本研究的目的是评估PsA患者的性功能及性功能障碍（SD）的患病率。
这是一项在单中心进行的观察性横断面研究，对23例PsA患者（男性12例；女性11例）进行评估，使用了两份针对巴西葡萄牙语验证的男性问卷（MSQ =男性性功能商数，IIEF =国际勃起功能指数）和两份女性问卷（FSQ =女性性功能商数，FSFI =女性性功能指数），以确定性功能的变化。还分析了临床参数、肌肉骨骼活动和皮肤活动，以确定与SD相关的因素。
男性的平均年龄为52.1±9.7岁，女性为49.1±9.6岁。临床上，患者的皮肤和外周关节疾病活动度低或处于缓解期。PsA的平均病程为10±6.2年，65.2%的患者有固定性伴侣。MSQ的平均得分是75.8±16.8。男性中SD的患病率为91.7%（IIEF），以轻度SD为主。FSQ的平均得分是64.9±24.1。女性中SD的患病率为72.7%（FSFI），各领域得分较低。此外，还发现女性年龄与FSFI总分及各领域得分之间存在显著关联。银屑病面积和严重程度指数（PASI）与总体满意度领域（IIEF）显著相关。
本研究发现PsA患者中SD的患病率很高。年龄对女性性功能有负面影响。医生需要更加关注该人群中的SD，以便提供早期多学科治疗，并尽量减少疾病对患者及其伴侣生活质量的影响。
