Wu Ying-Jie, Xiong Jian, Xiao Gui-Xiang, Tian Yuan, Yue Jian-Xin, Cheng Qing, Wang Miao, Zhou Liu-Qing, Zhou Tao
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Department of Otorhinolaryngology, People's Hospital of Dongxihu District, Wuhan, Hubei 430040, China.
Ear Nose Throat J. 2023 Apr 24:1455613231171832. doi: 10.1177/01455613231171832.
Salivary duct carcinoma (SDC) is an uncommon but highly aggressive tumor with a poor prognosis. SDC mainly arises from the major salivary glands, typically the parotid gland. Here, we report a rare case of sinonasal SDC in a 54-year-old male patient that might have originated from the inferior turbinate. The patient presented with left nasal congestion and rhinorrhea. Following an endoscopic intervention, the histopathological examination revealed a diagnosis of SDC, characterized by the formation of solid cancer nests and central comedo-type necrosis. Given the highly aggressive nature and unfavorable prognosis of SDC, it is essential to consider it as a differential diagnosis for unilateral nasal tumors.
涎腺导管癌（SDC）是一种罕见但侵袭性很强、预后较差的肿瘤。SDC主要起源于大唾液腺，通常是腮腺。在此，我们报告一例罕见的鼻窦SDC病例，患者为一名54岁男性，肿瘤可能起源于下鼻甲。患者表现为左侧鼻塞和流涕。经过内镜干预后，组织病理学检查确诊为SDC，其特征为形成实性癌巢和中央粉刺样坏死。鉴于SDC具有高度侵袭性且预后不良，将其作为单侧鼻腔肿瘤的鉴别诊断至关重要。
