Ge Hongjin
Department of Thoracic Surgery, Tianchang People's Hospital, Tianchang, Anhui Province, China.
Evid Based Complement Alternat Med. 2023 Apr 13;2023:8026918. doi: 10.1155/2023/8026918. eCollection 2023.
To explore the effect of amiodarone and cedilan in the treatment of patients with arrhythmia after esophageal and lung cancer.
The data of 60 patients with postoperative complications of arrhythmias after esophageal and lung cancer from January 2018 to July 2021 were retrospectively analyzed and divided into an observation group ( = 30) and control group ( = 30) according to the random number grouping principle. The former group was treated with amiodarone, and the latter group received cedilan.
The effective rate of treatment was significantly higher in the observation group than the control group ( < 0.05). The observation group had the drug onset time obviously shorter than the control group ( < 0.001). The average ventricular rate after treatment in the observation group was remarkably lower than the control group ( < 0.001). The observation group exhibited obviously better cardiac function after treatment as compared to the control group ( < 0.05). The incidence of adverse reactions in the observation group was notably lower than the control group ( < 0.05). Moreover, the observation group had less stress after treatment than the control group ( < 0.001). The blood pressure level of the observation group after treatment was significantly better than the control group ( < 0.05).
Amiodarone can relieve stress in patients with arrhythmia following esophageal and lung cancer surgery, stabilize blood pressure, and mitigate arrhythmia symptoms. Our findings are worthy of promotion and application in clinic.
探讨胺碘酮与西地兰治疗食管癌和肺癌术后心律失常患者的效果。
回顾性分析2018年1月至2021年7月60例食管癌和肺癌术后心律失常并发症患者的数据，根据随机数字分组原则分为观察组（n = 30）和对照组（n = 30）。前一组用胺碘酮治疗，后一组接受西地兰治疗。
观察组治疗有效率显著高于对照组（P < 0.05）。观察组药物起效时间明显短于对照组（P < 0.001）。观察组治疗后平均心室率显著低于对照组（P < 0.001）。与对照组相比，观察组治疗后心功能明显更好（P < 0.05）。观察组不良反应发生率明显低于对照组（P < 0.05）。此外，观察组治疗后应激比对照组少（P < 0.001）。观察组治疗后血压水平明显优于对照组（P < 0.05）。
胺碘酮可缓解食管癌和肺癌手术后心律失常患者的应激，稳定血压，减轻心律失常症状。我们的研究结果值得在临床上推广应用。
