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印度西部女性型脱发临床流行病学特征及其与代谢综合征相关性的横断面观察研究

A Cross-Sectional, Observational Study of the Clinico-Epidemiological Profile of Female Pattern Hair Loss in Western India and its Association with Metabolic Syndrome.

作者信息

Singh Shreya, Makhecha Meena B

机构信息

Department of Dermatology, HBTMC and Dr. R. N. Cooper Municipal General Hospital, Mumbai, Maharashtra, India.

出版信息

Indian Dermatol Online J. 2023 Feb 23;14(2):226-231. doi: 10.4103/idoj.idoj_360_22. eCollection 2023 Mar-Apr.

Abstract

BACKGROUND

The increasing prevalence of female pattern hair loss (FPHL) is an alarming concern. There are many studies on FPHL in the world literature but there is a dearth of Indian data on the same.

AIMS AND OBJECTIVES

The present study aims to ascertain the demographic variables and clinical features of FPHL in Western India and its association with metabolic syndrome (MetS) to add over and above the existing data.

MATERIALS AND METHODS

Ninety females who were diagnosed with FPHL were included after approval of the institutional ethics committee. Demographic details, detailed history, and clinical features were noted, following which a few blood investigations for diagnosis of MetS were advised and evaluated.

RESULTS

Our study population's age ranged from 17 to 65 years, with the mean age of 34.7 ± 1.3 years. According to the Basic and Specific (BASP) classification, The basic pattern prevalence as found in our study was 46.7% for M type, 35.6% for L type, and 17.7% for C type. The FPHL severity score revealed that 82 (91.1%) had advanced disease at presentation. Prevalence of MetS was found to be 34.4% and had a significant correlation with age of onset in years (p=0.041) and severity score (p=0.013) implying that it leads to an early onset and greater severity of FPHL.

CONCLUSION

FPHL is increasingly common among Indian women, who frequently present with a bitemporal recession of the hairline. Calculation of the female pattern hair loss severity index (FPHL-SI) can help in the categorization of patients and assessment of prognosis. MetS should be actively looked for in patients of FPHL and managed accordingly.

摘要

背景

女性型脱发(FPHL)患病率的不断上升是一个令人担忧的问题。世界文献中有许多关于FPHL的研究,但印度在这方面的数据却很匮乏。

目的

本研究旨在确定印度西部FPHL的人口统计学变量和临床特征及其与代谢综合征(MetS)的关联,以补充现有数据。

材料与方法

经机构伦理委员会批准后,纳入90例被诊断为FPHL的女性。记录人口统计学细节、详细病史和临床特征,随后建议并评估一些用于诊断MetS的血液检查。

结果

我们的研究人群年龄在17至65岁之间,平均年龄为34.7±1.3岁。根据基本和特殊(BASP)分类,我们研究中发现的基本模式患病率为M型46.7%,L型35.6%,C型17.7%。FPHL严重程度评分显示,82例(91.1%)在就诊时患有晚期疾病。MetS的患病率为34.4%,与发病年龄(p=0.041)和严重程度评分(p=0.013)显著相关,这意味着它会导致FPHL的早发和更严重程度。

结论

FPHL在印度女性中越来越普遍,她们经常表现为双侧颞部发际线后移。计算女性型脱发严重程度指数(FPHL-SI)有助于对患者进行分类和评估预后。应积极在FPHL患者中寻找MetS并进行相应管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/441c/10115337/f1cf6d4602a1/IDOJ-14-226-g001.jpg

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