Seino Hiroaki, Onishi Yukiko, Eguchi Kosei, Nishijima Keiji, Sato Toshihiro, Shirabe Shinichiro
Seino Internal Medicine Clinic, 6-192-2 Kaisei, Koriyama, Fukushima 963-8851 Japan.
The Institute of Medical Science, Asahi Life Foundation, Tokyo, Japan.
Diabetol Int. 2023 Jan 14;14(2):172-182. doi: 10.1007/s13340-022-00612-y. eCollection 2023 Apr.
CAPTURE was a cross-sectional, non-interventional study (NCT03786406, NCT03811288) investigating the prevalence and characteristics of cardiovascular disease (CVD) in adults with type 2 diabetes (T2D) across 13 countries worldwide. Here we present the findings for Japan.
Data were collected from adults aged ≥ 20 years (aged ≥ 18 years in countries outside Japan) with T2D who were managed in clinics or hospitals in 2019. Standardized methodology was used for all countries. The prevalence of CVD and its subtypes was estimated, weighted by care setting (clinics versus hospitals).
Among participants from Japan (total: 800; clinics: 440; hospitals: 360), mean (standard deviation) age was 65.6 (11.2) years and glycated hemoglobin 7.2% (0.9). Sixty-seven percent of participants were male, 57.8% had diabetes duration > 10 years, 49.8% had body mass index ≥ 25 kg/m and 63.1% had hypertension. The weighted prevalences (95% confidence interval [CI]) of CVD and atherosclerotic CVD were 37.3% (34.2;40.3) and 33.5% (30.6;36.4), respectively. The prevalence (95% CI) of the most common subtypes of CVD was: carotid artery disease 20.5% (18.2;22.8), coronary heart disease 11.9% (9.7;14.1) and cerebrovascular disease 10.4% (8.3;12.5).
These contemporary data from the CAPTURE study on CVD prevalence in adults with T2D in Japan show that approximately one in three adults with T2D had established CVD, which is comparable to the prevalence in the global study cohort.
The online version contains supplementary material available at 10.1007/s13340-022-00612-y.
CAPTURE是一项横断面非干预性研究（NCT03786406，NCT03811288），旨在调查全球13个国家中2型糖尿病（T2D）成人患者心血管疾病（CVD）的患病率及特征。在此，我们展示日本的研究结果。
收集2019年在诊所或医院接受治疗的年龄≥20岁（日本以外国家为≥18岁）的T2D成人患者的数据。所有国家均采用标准化方法。估算CVD及其亚型的患病率，并根据治疗机构（诊所与医院）进行加权。
在来自日本的参与者中（总计800人；诊所440人；医院360人），平均（标准差）年龄为65.6（11.2）岁，糖化血红蛋白为7.2%（0.9）。67%的参与者为男性，57.8%的患者糖尿病病程>10年，49.8%的患者体重指数≥25kg/m，63.1%的患者患有高血压。CVD和动脉粥样硬化性CVD的加权患病率（95%置信区间[CI]）分别为37.3%（34.2；40.3）和33.5%（30.6；36.4）。CVD最常见亚型的患病率（95%CI）为：颈动脉疾病20.5%（18.2；22.8），冠心病11.9%（9.7；14.1），脑血管疾病10.4%（8.3；12.5）。
CAPTURE研究中关于日本T2D成人患者CVD患病率的这些当代数据表明，约三分之一的T2D成人患者已患有CVD，这与全球研究队列中的患病率相当。
在线版本包含可在10.1007/s13340-022-00612-y获取的补充材料。
