Nakagawa Hibiki, Aramaki Toshihiro, Kondo Shigeru, Kuroda Junpei
Graduate school of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.
MicroPubl Biol. 2023 Apr 7;2023. doi: 10.17912/micropub.biology.000747. eCollection 2023.
Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that ( ) gene product is essential for the regular arrangement of actinotrichia using -knockout zebrafish. Here, we examined the localization pattern of the EGFP-tagged Col9a1c protein in the fins to understand its role in the arrangement of actinotrichia. We found that EGFP-Col9a1c specifically localizes to actinotrichia.
硬骨鱼的鳍由称为鳍条的矛状胶原晶体支撑。鳍条呈放射状分布在鳍的远端，被认为是鳍和鳍骨正常形成所必需的。我们之前报道过，使用 -敲除斑马鱼，（ ）基因产物对于鳍条的规则排列至关重要。在这里，我们检测了鳍中EGFP标记的Col9a1c蛋白的定位模式，以了解其在鳍条排列中的作用。我们发现EGFP-Col9a1c特异性定位于鳍条。
