Choudhary Sidhya, Mishra Ramesh Kumar, Pathan Nazneen, Vyas Aruna, Sharma Shashank, Gupta Karuna
Department of Microbiology, SMS Medical College, Jaipur, Rajasthan, India.
Department of Radiodiagnosis, SMS Medical College, Jaipur, Rajasthan, India.
Med Mycol Case Rep. 2023 Mar 29;40:36-39. doi: 10.1016/j.mmcr.2023.03.004. eCollection 2023 Jun.
A 70-year-old female presented with left sided low back pain. There was no history of any co-morbidities or immunocompromised state. Skeletal cryptococcosis was confirmed bsaed on culture and histopathology, along with pulmonary involvement. After a month of oral antifungal therapy, the patient's symptoms resolved, but an abscess relapsed at the same site, which was treated with a combination of IV Amphotericin B and 5-flucytosine followed by oral fluconazole, with no recurrence or complaints reported in subsequent follow-up.
一名70岁女性因左侧下背部疼痛就诊。无任何合并症或免疫功能低下状态史。根据培养和组织病理学检查确诊为骨骼隐球菌病,同时伴有肺部受累。经过一个月的口服抗真菌治疗,患者症状缓解,但同一部位脓肿复发,采用静脉注射两性霉素B和5-氟胞嘧啶联合治疗,随后口服氟康唑,后续随访未报告复发或不适。