Gill G V, Huddle K R, Krige L P
Diabetes Res. 1986 Mar;3(3):145-8.
In order to explore the feasibility of home blood glucose monitoring (HBGM) in Type 1 diabetics in developing countries, we introduced the technique to Type 1 patients below the age of 30 yr attending the Diabetic Clinic serving Soweto in South Africa. Despite initial problems, HBGM with visually-read strips was applied to 45 of the 64 young Type 1 diabetics identified ("HBGM group"). The remaining 19 were continued on urine glucose monitoring only ("HUGM group"), usually because of attendance and compliance problems. After 4 months' follow-up, glycosylated haemoglobin (HbA1) fell from 10.5 +/- 2.6% (mean +/- SD) to 9.0 +/- 1.7 (p less than 0.001) in the HBGM group, but was unchanged (10.1 +/- 2.1 vs 9.9 +/- 1.9, pn.s.) in HUGM patients. HBGM can thus be introduced in adverse social conditions, and may be associated with improved diabetic control. Costs, in terms of finance and medical time, were not excessive. Unfortunately, a significant minority were excluded by attendance and other problems, and analysis of diabetic complication rates (before the programme began) showed that these patients had significantly more complications than those deemed suitable for HBGM (42.1% vs 15.5%, p less than 0.05).
为了探索在发展中国家1型糖尿病患者中进行家庭血糖监测(HBGM)的可行性,我们将该技术引入了南非索韦托糖尿病诊所就诊的30岁以下1型患者。尽管最初存在问题,但使用视觉读数试纸的HBGM应用于64名确诊的年轻1型糖尿病患者中的45名(“HBGM组”)。其余19名患者仅继续进行尿糖监测(“HUGM组”),通常是因为就诊和依从性问题。经过4个月的随访,HBGM组糖化血红蛋白(HbA1)从10.5±2.6%(均值±标准差)降至9.0±1.7(p<0.001),但HUGM组患者糖化血红蛋白无变化(10.1±2.1对比9.9±1.9,p无统计学意义)。因此,在不利的社会条件下也可引入HBGM,且可能与改善糖尿病控制有关。在资金和医疗时间方面,成本并不高。不幸的是,相当一部分患者因就诊及其他问题被排除在外,并且(在项目开始前)对糖尿病并发症发生率的分析显示,这些患者的并发症明显多于那些被认为适合进行HBGM的患者(42.1%对比15.5%,p<0.05)。