General Surgery and Trauma Team, ASST Niguarda, Piazza Ospedale Maggiore 3Milano, 20162, Milan, Italy.
Division of General Surgery, Department of Translational Medicine, Maggiore Della Carità Hospital, University of Eastern Piedmont, Corso Giuseppe Mazzini 18, Novara, Italy.
Updates Surg. 2022 Jun;74(3):1129-1136. doi: 10.1007/s13304-021-01131-2. Epub 2021 Sep 13.
Alcohol and drugs misuse represents an important social problem. There is no agreement about influence of ethanol and drugs on trauma severity and clinical course. The aim of this study was to investigate the impact of alcohol and drugs abuse on road related trauma managed to our Level I Trauma Center. Data of 1067 car or motorcycle drivers consecutively admitted in a 5 years period were retrospectively analyzed. The sample was divided into two groups: patients with alcohol and/or drugs misuse and patients without detectable plasmatic levels or not screened because no clinical suspicion of these substance. Demographic data, mechanism of trauma, severity of injury, daily and season time of trauma distribution, alcohol and drugs levels and outcomes were retrieved. Alcohol or drugs misuse were detected in 242 patients. Heavy alcohols levels were the 62.3%. Among drugs cannabis was the most detected substance. These patients were significantly younger than the overall study population (p = 0.011), with a higher ISS (p = 0.012) a lower RTS (p = 0.047), a lower GCS (p = 0.005) and an higher head injuries severity (p = 0.030). Regarding time distribution, Saturday was the day with the highest percentage of trauma associated with substance misuse (21%). Alcohol/drugs misuse plays a very important role in the epidemiology of road related trauma. Despite the higher severity of trauma scores and the higher incidence of severe head injuries in patients with alcohol or drugs consumption, there were no effects of this substances on mortality of injured patients involved in road crashes.
酒精和药物滥用是一个重要的社会问题。目前对于乙醇和药物对创伤严重程度和临床病程的影响尚无定论。本研究旨在调查酒精和药物滥用对我院一级创伤中心诊治的道路相关创伤的影响。回顾性分析了连续 5 年收治的 1067 名汽车或摩托车驾驶员的数据。将样本分为两组:酒精和/或药物滥用患者组和未检测到血浆水平或因无这些物质临床怀疑而未筛查的患者组。检索了人口统计学数据、创伤机制、损伤严重程度、创伤发生的日常和季节性时间、酒精和药物水平以及结果。在 242 名患者中检测到酒精或药物滥用。酒精浓度高的有 62.3%。在检测到的药物中,大麻是最常见的物质。这些患者明显比总体研究人群年轻(p=0.011),ISS 更高(p=0.012),RTS 更低(p=0.047),GCS 更低(p=0.005),头部损伤严重程度更高(p=0.030)。就时间分布而言,星期六是与物质滥用相关创伤发生率最高的一天(21%)。酒精/药物滥用在道路相关创伤的流行病学中起着非常重要的作用。尽管在有酒精或药物使用的患者中,创伤评分的严重程度更高,严重头部损伤的发生率更高,但这些物质对道路交通事故中受伤患者的死亡率没有影响。