Romero Carolina S, Maimeri Nicolò, Bonaccorso Alessandra, Baiardo-Redaelli Martina, Lombardi Gaetano, Iwuchukwu Otito Frances, Ortalda Alessandro, Schmid Benedikt, Fleming Magdalena, Landoni Giovanni
Department of Anesthesia, Critical Care and Pain Unit, University General Hospital, Spain.
Department of Methods in Research, European University of Valencia, Valencia, Spain.
Contemp Clin Trials Commun. 2023 Apr 2;33:101117. doi: 10.1016/j.conctc.2023.101117. eCollection 2023 Jun.
Women researchers might experience obstacles in academic environments and might be underrepresented in the authorship of articles published in peer-reviewed journals.
This is a cross-sectional analysis of female-led RCTs describing all interventions reducing mortality in critically ill and perioperative patients from 1981 to December 31, 2020. We searched PubMed/MEDLINE and EMBASE with the keywords RCTs and mortality. The gender of the first author was extracted and descriptive analysis was performed including the year of publication, impact factor, country of the first author, and methodological aspects.
We analyzed 340 RCTs, of which 42 (12%) were led by female researchers. The presence of women increased from 8% (14/172) until 2010 up to 17% (28/168) in 2010 and beyond. The United States, the United Kingdom, and Brazil were the main countries of origin of female researchers. Women authors conducted mainly single-center and single-nation studies as compared to male authors. The median impact factor of the target journal was 6 (3-27) in women vs. 7 (3-28) in men, with a p-value of 0.67; , , and were the most frequent target journals for both women and men.
In the last 40 years, only one out of eight RCTs had a woman as the first author but the presence of women increased up to 17% by 2010 and beyond. The impact factor of publication target journals was high and not different between genders.
女性研究人员在学术环境中可能会遇到障碍，并且在同行评审期刊上发表文章的作者中所占比例可能较低。
这是一项对女性主导的随机对照试验（RCT）的横断面分析，描述了1981年至2020年12月31日期间所有降低危重症和围手术期患者死亡率的干预措施。我们使用关键词“随机对照试验”和“死亡率”在PubMed/MEDLINE和EMBASE中进行检索。提取第一作者的性别，并进行描述性分析，包括发表年份、影响因子、第一作者所在国家以及方法学方面。
我们分析了340项随机对照试验，其中42项（12%）由女性研究人员主导。女性主导的试验比例从2010年之前的8%（14/172）上升到2010年及之后的17%（28/168）。美国、英国和巴西是女性研究人员的主要来源国。与男性作者相比，女性作者主要进行单中心和单国家研究。女性作者所发表文章的目标期刊的影响因子中位数为6（3 - 27），男性为7（3 - 28），p值为0.67；女性和男性最常发表文章的目标期刊都是 、 和 。
在过去40年中，八分之一的随机对照试验的第一作者为女性，但到2010年及之后，女性主导的试验比例上升到了17%。发表文章的目标期刊的影响因子较高，且不同性别之间没有差异。
