Manfreda J, Holford-Strevens V, Cheang M, Warren C P
Environ Health Perspect. 1986 Apr;66:73-80. doi: 10.1289/ehp.866673.
History of acute symptoms (cough, wheezing, shortness of breath, fever, stuffy nose, and skin itching/rash) following exposure to grain dust was obtained from 661 male and 535 female current and former farmers. These symptoms were relatively common: 60% of male and 25% of female farmers reported at least one such symptom on exposure to grain dust. Association of cough, wheezing, shortness of breath, and stuffy nose with skin reactivity and capacity to form IgE is consistent with an allergic nature of these symptoms. Barley and oats dust were perceived as dust most often producing symptoms. On the other hand, grain fever showed a different pattern, i.e., it was not associated with either skin reactivity or total IgE. Smoking might modify the susceptibility to react to grain dust with symptoms. Only those who reported wheezing on exposure to grain dust may have an increased risk to develop chronic airflow obstruction.
我们从661名男性和535名女性在职及离职农民那里了解到了他们接触谷物粉尘后出现急性症状（咳嗽、喘息、呼吸急促、发热、鼻塞以及皮肤瘙痒/皮疹）的病史。这些症状相对较为常见：60%的男性农民和25%的女性农民报告称，在接触谷物粉尘后至少出现过一种此类症状。咳嗽、喘息、呼吸急促和鼻塞与皮肤反应性及形成IgE的能力之间的关联，与这些症状的过敏性质相符。大麦和燕麦粉尘被认为是最常引发症状的粉尘。另一方面，谷尘热呈现出不同的模式，即它与皮肤反应性或总IgE均无关联。吸烟可能会改变对谷物粉尘产生症状反应的易感性。只有那些报告在接触谷物粉尘时出现喘息症状的人，患慢性气流阻塞的风险可能会增加。
