Cockcroft A E, McDermott M, Edwards J H, McCarthy P
Eur J Respir Dis. 1983 Apr;64(3):189-96.
Eighty dock workers handling grains and other cargoes were surveyed by respiratory and occupational questionnaires, spirometry, skin tests with common allergens and grain extracts, and serological tests. Sixty-nine of the men reported chest symptoms during exposure to barley dust and 13 men reported evening feverish episodes after handling barley. Symptoms were not related to smoking or atopic status. No gross deficits in lung function were detected. Six men handling barley and four handling non-dusty cargoes had their lung function measured over two working days. Falls in ventilatory capacity occurred in the six workers handling barley but not in the four handling non-dusty cargoes. Six previously unexposed subjects spent 2 h in a barley dust atmosphere of a silo and had lung function measured before and after the exposure. All subjects had falls in ventilatory capacity. In four these lasted 24 h or more and were associated with systemic symptoms. As with cotton dust the agent(s) responsible for symptoms from grain dust exposure remains uncertain. Our findings on the dock workers suggest that specific immunological responses are not involved.
通过呼吸和职业调查问卷、肺活量测定、使用常见变应原和谷物提取物进行皮肤试验以及血清学检测，对80名处理谷物和其他货物的码头工人进行了调查。其中69名男性报告在接触大麦粉尘时有胸部症状，13名男性报告在处理大麦后出现夜间发热。症状与吸烟或特应性状态无关。未检测到明显的肺功能缺陷。对6名处理大麦的工人和4名处理无粉尘货物的工人在两个工作日内进行了肺功能测量。处理大麦的6名工人出现了通气能力下降，但处理无粉尘货物的4名工人未出现。6名以前未接触过的受试者在筒仓的大麦粉尘环境中呆了2小时，并在接触前后测量了肺功能。所有受试者的通气能力均下降。其中4人的通气能力下降持续了24小时或更长时间，并伴有全身症状。与棉尘一样，谷物粉尘暴露所致症状的致病因子仍不确定。我们对码头工人的研究结果表明，不涉及特异性免疫反应。
