Research Center for Implementation Nursing Science Initiative, Fujita Health University, Toyoake, Japan.
Department of Nursing, Fujita Health University Hospital, Toyoake, Japan.
Int Wound J. 2023 Oct;20(8):3289-3297. doi: 10.1111/iwj.14209. Epub 2023 Apr 24.
We aimed to investigate the association between the presence of cutaneous urease-producing bacteria and the development of incontinence-associated dermatitis (IAD) using an original urea agar medium as a step toward developing advanced preventive measures. In previous clinical assessments, we developed an original urea agar medium to detect urease-producing bacteria via the medium's colour changes. In a cross-sectional study, specimens were collected via the swabbing technique at genital skin sites in 52 stroke patients hospitalised in a university hospital. The primary objective was to compare the presence of urease-producing bacteria between the IAD and no-IAD groups. Determining the bacterial count was the secondary objective. The prevalence of IAD was 48%. A significantly higher detection rate of urease-producing bacteria was observed in the IAD group than in the no-IAD group (P = .002) despite the total number of bacteria being equivalent between them. In conclusion, we discovered that there was a significant association between the presence of urease-producing bacteria and IAD development in hospitalised stroke patients.
我们旨在使用原始尿素琼脂培养基研究产尿素酶细菌的存在与失禁相关性皮炎(IAD)发展之间的关系,以期开发出更先进的预防措施。在之前的临床评估中,我们开发了一种原始尿素琼脂培养基,通过培养基的颜色变化来检测产尿素酶细菌。在一项横断面研究中,我们通过拭子技术在一家大学医院的 52 名中风住院患者的生殖器皮肤部位采集标本。主要目标是比较 IAD 组和非 IAD 组中产尿素酶细菌的存在情况。次要目标是确定细菌计数。IAD 的患病率为 48%。尽管两组的细菌总数相当,但 IAD 组中产尿素酶细菌的检测率明显高于非 IAD 组(P = .002)。总之,我们发现,在住院中风患者中,产尿素酶细菌的存在与 IAD 的发展之间存在显著关联。