Venturini P L, Horowski R, Valenzano M, Costantini S, Fasce V, Gorlero F, Rainer E, De Cecco L
Eur J Clin Pharmacol. 1986;30(2):195-7. doi: 10.1007/BF00614302.
Terguride, is an 8 - alpha - ergoline derived from lisuride, acts as a partial dopamine (DA) agonist. The effect and tolerance of terguride has been investigated by an acute administration of 0.2 mg p.o. to 8 normal women, 8 patients with hyperprolactinaemia and 8 women with puerperal hyperprolactinaemia. Prolactin (PRL) levels were markedly suppressed in all subjects, with no significant differences between the groups. Treatment for 5 days with terguride 0.4 mg/day or 0.8 mg/day was studied as an inhibitor of lactation. PRL levels were suppressed in a dose-related manner. No untoward side-effects were noted.
泰舒达是一种从利苏瑞得衍生而来的8-α-麦角灵，作为一种多巴胺（DA）部分激动剂。通过对8名正常女性、8名高泌乳素血症患者和8名产后高泌乳素血症女性口服0.2毫克进行急性给药，研究了泰舒达的效果和耐受性。所有受试者的催乳素（PRL）水平均显著降低，各组之间无显著差异。研究了以0.4毫克/天或0.8毫克/天的泰舒达治疗5天作为泌乳抑制剂的情况。PRL水平呈剂量依赖性降低。未观察到不良副作用。
