Departamento de Matemática, Física y Estadística, Facultad de Ciencias Básicas, Universidad Católica del Maule, Talca 3480112, Chile.
Departamento de Matemática, Física y Estadística, Facultad de Ciencias Básicas, Universidad Católica del Maule, Talca 3480112, Chile.
Acta Trop. 2023 Jul;243:106930. doi: 10.1016/j.actatropica.2023.106930. Epub 2023 Apr 23.
Chagas disease is caused by the protozoan Trypanosoma cruzi, which parasitizes many mammals, including humans. Its vectors are blood-feeding hematophagous triatomine insects of different species, which vary according to the geographical area. One of the 17 neglected diseases targeted by the World Health Organization, Chagas disease is endemic to the Americas, but has spread to other countries due to human migratory movements. In this study, we describe the epidemiological dynamics of Chagas disease in an endemic area, considering the main transmission mechanisms and the demographic effects of birth, mortality, and human migration in this phenomenon. We apply mathematical models as a methodological approach to simulate the interactions between reservoirs, vectors, and humans using a system of ordinary differential equations. The results show that the Chagas disease control measures currently in place cannot be relaxed without endangering the progress achieved to date.
恰加斯病由原生动物克氏锥虫引起，这种寄生虫寄生在许多哺乳动物中，包括人类。其传播媒介是不同物种的吸血性半翅目昆虫，这些昆虫因地理区域而异。恰加斯病是世界卫生组织针对的 17 种被忽视疾病之一，该病流行于美洲，但由于人类的迁移运动已传播到其他国家。在这项研究中，我们考虑了主要的传播机制以及出生、死亡和人类迁移对这一现象的人口效应，描述了流行地区的恰加斯病的流行病学动态。我们应用数学模型作为一种方法学方法，使用常微分方程组来模拟储主、媒介和人类之间的相互作用。结果表明，如果不危及迄今取得的进展，目前实施的恰加斯病控制措施就不能放松。
