Ruhr University Bochum, Bleichstr. 15, 44787, Bochum, Germany.
Helios Klinikum München West, Steinerweg 5, 81241, Munich, Germany.
Health Qual Life Outcomes. 2023 Apr 25;21(1):37. doi: 10.1186/s12955-023-02118-w.
Quality of life questionnaires are often used in the assessment of rehabilitation of hearing-impaired patients with a cochlear implant. However, a prospective study with a systematic retrospective evaluation of the preoperative quality of life after surgery has not yet been conducted and may reveal a change in internal standards, such as a response shift, due to the implantation and hearing rehabilitation.
The Nijmegen Cochlear Implant Questionnaire (NCIQ) was used for assessing hearing related quality of life. It has three general domains (physical, psychological and social) and six subdomains. Seventeen patients were tested before (t) and retrospectively (then-test; pre-t) and acutely postoperative (post-t) after cochlear implantation. Observed changes, then-test changes, response shifts and effect sizes were calculated. Non-parametric statistical methods were used.
The NCIQ total score was 52.32 ± 18.69 (mean, standard deviation) for t, 59.29 ± 14.06 for pre-t and 67.65 ± 26.02 for post-t questioning. The observed change was statistically significant in all domains but in speech production. Response shift was statistically significant in the total score and in part of the domains. The effect sizes for the response shift were moderate (> 0.5) in the total score, psychological, social general scores and subdomains.
In this study we found that response shift does exist in adults with severe to profound hearing loss undergoing cochlear implantation. By advising the participants to deactivate the implant for the then-test, recall bias and noise were minimized. The clinical significance of the response shift was present in the total score and in the social and psychological domains.
This study was retrospectively registered with the German Clinical Trial Register, TRN DRKS00029467, on 07/08/2022.
生活质量问卷常用于评估植入人工耳蜗的听力受损患者的康复情况。然而，目前尚未进行前瞻性研究，对手术后的术前生活质量进行系统回顾性评估，这可能会因为植入和听力康复而导致内部标准发生变化，例如反应转移。
采用奈梅亨人工耳蜗植入问卷（NCIQ）评估与听力相关的生活质量。它有三个一般领域（身体、心理和社会）和六个子领域。17 名患者在植入前（t）和回顾性（then-test；pre-t）和急性术后（post-t）接受了测试。计算观察到的变化、then-test 变化、反应转移和效应量。使用非参数统计方法。
NCIQ 总分为 t 时的 52.32±18.69（平均值，标准差），pre-t 时为 59.29±14.06，post-t 时为 67.65±26.02。所有领域（除言语产生外）的观察到的变化均具有统计学意义。反应转移在总分和部分领域具有统计学意义。反应转移的效应量在总分和心理、社会总评分和子领域中为中度（>0.5）。
在这项研究中，我们发现对严重至重度听力损失患者进行人工耳蜗植入后确实存在反应转移。通过建议参与者在 then-test 时停用植入物，最小化了回忆偏差和噪音的影响。反应转移的临床意义存在于总分和社会及心理领域。
本研究于 2022 年 07 月 08 日在德国临床试验注册中心（TRN DRKS00029467）进行了回顾性注册。
