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[各种阳离子对胃分泌及产酸功能的影响]

[Effect of various cations on the secretory and acid-forming function of the stomach].

作者信息

Bakuradze A N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Apr;72(4):549-52.

PMID:3709882
Abstract

The data obtained suggest that the sodium ions (0.5-2.0 g) reduce the gastric juice secretion and its acidity whereas magnesium and calcium ions increase the latter. Potassium ions exert practically no effect on the acidity. The suppressing effect of the sodium ions seems to be connected with an increase excretion of sodium chloride with urine as well as with increased diuresis in general. Saluretics suppress the secretion and acidity of the gastric juice on account of increased diuresis and subsequent excretion of large amount of chlorides as well as by means of serotonin release from the Ec cells of the gastro-intestinal tract, the action of serotonin being actualized on the level of the gastric glands' cells, parietal those in particular.

摘要

所获得的数据表明,钠离子(0.5 - 2.0克)会减少胃液分泌及其酸度,而镁离子和钙离子则会增加胃液酸度。钾离子对胃液酸度几乎没有影响。钠离子的抑制作用似乎与尿中氯化钠排泄增加以及总体利尿增加有关。利尿剂由于利尿增加以及随后大量氯化物的排泄,还通过胃肠道Ec细胞释放血清素,血清素在胃腺细胞尤其是壁细胞水平上发挥作用,从而抑制胃液的分泌和酸度。

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