Darsee J R
South Med J. 1979 Feb;72(2):174-80. doi: 10.1097/00007611-197902000-00017.
Embolization of cholesterol crystals from ulcerated atheromatous lesions can produce distinct syndromes that mimic more common disease processes. Cholesterol emboli can present as renal failure, hypertension, spells of numbness, abdominal pain, and myocardial infarction, or as a multisystem disease that closely approximates the presentation, clinical course, and even biopsy picture of polymyositis or periarteritis nodosa. A review of this problem with particular attention to the clinical presentations should help in the early diagnosis and treatment of cholesterol emboli and avoid unnecessary and inappropriate therapies.
来自溃疡性动脉粥样硬化病变的胆固醇结晶栓塞可产生独特的综合征,这些综合征类似于更常见的疾病过程。胆固醇栓子可表现为肾衰竭、高血压、麻木发作、腹痛和心肌梗死,或表现为一种多系统疾病,其临床表现、临床病程甚至活检图像与多发性肌炎或结节性多动脉炎极为相似。对这一问题进行综述并特别关注临床表现,应有助于胆固醇栓子的早期诊断和治疗,并避免不必要和不恰当的治疗。