Shoenut J P, Micflikier A B
Gastrointest Endosc. 1986 Apr;32(2):84-7. doi: 10.1016/s0016-5107(86)71762-8.
A controlled trial was conducted to determine the etiology of retrosternal pain following sclerotherapy. Sclerotherapy was performed on patients that had previously bled from varices. Esophageal motility studies were recorded from seven patients prior to sclerotherapy and immediately subsequent (within 10 min) to it. Motility studies were also recorded from seven normal subjects before and after undergoing gastroscopy to determine the effects of gastroscopy upon esophageal motility. Sclerotherapy appears to induce a transient pattern of diffuse esophageal spasm, the main features of which are significantly (p less than 0.05) prolonged wave duration, increased peak amplitude, and simultaneous contractions.
进行了一项对照试验，以确定硬化疗法后胸骨后疼痛的病因。对先前因静脉曲张出血的患者进行了硬化疗法。在7例患者硬化疗法前及硬化疗法后立即（10分钟内）记录食管动力研究。还对7名正常受试者在接受胃镜检查前后记录动力研究，以确定胃镜检查对食管动力的影响。硬化疗法似乎会诱发一种弥漫性食管痉挛的短暂模式，其主要特征为波持续时间显著延长（p<0.05）、峰值振幅增加和同步收缩。
