Bovero E, Farese A
Department of Gastroenterology, Ospedale S. Martino, Genova, Italy.
Surg Endosc. 1988;2(3):156-8. doi: 10.1007/BF02498790.
Sclerotherapy of esophageal varices is an effective hemostatic treatment and may also prevent bleeding. In our study, we examined the effects of prophylactic sclerotherapy on esophageal motility in 15 patients with Child's A cirrhosis of the liver. All the patients underwent three manometric measurements, performed respectively before the sclerotherapy, 1 week after the eradication of varices, and 3 months later. The results of our study show that prophylactic sclerotherapy of esophageal varices does not significantly change the resting pressure and length of the lower esophageal sphincter. Neither the amplitude nor the duration of the postswallowing esophageal peristaltic waves is significantly influenced by sclerotherapy. However, sclerotherapy produces a significant increase in tertiary contractions in the distal esophagus, which could explain the onset of dysphagia among patients in whom postsclerotherapy stricture is not evident.
食管静脉曲张硬化疗法是一种有效的止血治疗方法，也可能预防出血。在我们的研究中，我们检查了预防性硬化疗法对15例Child's A级肝硬化患者食管动力的影响。所有患者均接受了三次测压，分别在硬化疗法前、静脉曲张消除后1周以及3个月后进行。我们的研究结果表明，食管静脉曲张预防性硬化疗法不会显著改变食管下括约肌的静息压力和长度。硬化疗法对吞咽后食管蠕动波的幅度和持续时间均无显著影响。然而，硬化疗法会使食管远端的三级收缩显著增加，这可以解释硬化疗法后狭窄不明显的患者出现吞咽困难的原因。
