Alexander Daniel A, Certa Olivia, Haertter Allison, Li Taoran, Taunk Neil, Zhu Timothy C
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12371. doi: 10.1117/12.2652588. Epub 2023 Mar 6.
The emergence of the Halcyon linear accelerator has allowed for increased patient throughput and improved treatment times for common treatment sites in radiation oncology. However, it has been shown that this can lead to increased surface dose in sites like breast cancer compared with treatments on conventional machines with flattened radiation beams. Cherenkov imaging can be used to estimate surface dose by detection of Cherenkov photons emitted in proportion to energy deposition from high energy electrons in tissue. Phantom studies were performed with both square beams in reference conditions and with clinical treatments, and dosimeter readings and Cherenkov images report higher surface dose (25% for flat phantom entrance dose, 5.9% for breast phantom treatment) from Halcyon beam deliveries than for equivalent deliveries from a TrueBeam linac. Additionally, the first Cherenkov images of a patient treated with Halcyon were acquired, and superficial dose was estimated.
Halcyon直线加速器的出现提高了放射肿瘤学中常见治疗部位的患者通量并缩短了治疗时间。然而,研究表明,与使用扁平辐射束的传统机器进行治疗相比,这可能会导致乳腺癌等部位的表面剂量增加。切伦科夫成像可用于通过检测与组织中高能电子的能量沉积成比例发射的切伦科夫光子来估计表面剂量。在参考条件下使用方形光束和临床治疗进行了模体研究,剂量计读数和切伦科夫图像显示,与TrueBeam直线加速器的等效照射相比,Halcyon光束照射产生的表面剂量更高(平板模体入射剂量高25%,乳腺模体治疗高5.9%)。此外,还获取了接受Halcyon治疗的患者的首张切伦科夫图像,并估计了表面剂量。