• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Cherenkov imaging for total skin electron therapy (TSET).切伦科夫成像在全身电子束放射治疗（TSET）中的应用。
Med Phys. 2020 Jan;47(1):201-212. doi: 10.1002/mp.13881. Epub 2019 Nov 26.
2
Cherenkov imaging for Total Skin Electron Therapy - an evaluation of dose uniformity.用于全身皮肤电子线治疗的切伦科夫成像——剂量均匀性评估
Proc SPIE Int Soc Opt Eng. 2021 Mar;11628. doi: 10.1117/12.2583939. Epub 2021 Mar 30.
3
Improving treatment geometries in total skin electron therapy: Experimental investigation of linac angles and floor scatter dose contributions using Cherenkov imaging.提高全身电子治疗中的治疗几何形状：使用切伦科夫成像研究直线加速器角度和地板散射剂量的贡献。
Med Phys. 2018 Jun;45(6):2639-2646. doi: 10.1002/mp.12917. Epub 2018 May 6.
4
Cherenkov imaging method for rapid optimization of clinical treatment geometry in total skin electron beam therapy.用于全身皮肤电子束治疗中临床治疗几何形状快速优化的切伦科夫成像方法。
Med Phys. 2016 Feb;43(2):993-1002. doi: 10.1118/1.4939880.
5
Rapid Multisite Remote Surface Dosimetry for Total Skin Electron Therapy: Scintillator Target Imaging.快速多点远程表面剂量测定在全身皮肤电子治疗中的应用：闪烁体靶成像。
Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):767-774. doi: 10.1016/j.ijrobp.2018.10.030. Epub 2018 Nov 10.
6
Initial Clinical Experience of Cherenkov Imaging in External Beam Radiation Therapy Identifies Opportunities to Improve Treatment Delivery.切伦科夫成像在外照射放疗中的初步临床经验确定了改善治疗实施的机会。
Int J Radiat Oncol Biol Phys. 2021 Apr 1;109(5):1627-1637. doi: 10.1016/j.ijrobp.2020.11.013. Epub 2020 Nov 20.
7
Matching the dosimetry characteristics of a dual-field Stanford technique to a customized single-field Stanford technique for total skin electron therapy.将双野斯坦福技术的剂量学特征与定制的单野斯坦福技术用于全身皮肤电子治疗进行匹配。
Int J Radiat Oncol Biol Phys. 2004 Jul 1;59(3):872-85. doi: 10.1016/j.ijrobp.2004.02.046.
8
Monte Carlo (MC) study of dose distribution and Cherenkov imaging in total skin electron therapy (TSET) with TOPAS.使用TOPAS对全身皮肤电子线治疗（TSET）中的剂量分布和切伦科夫成像进行蒙特卡罗（MC）研究。
Proc SPIE Int Soc Opt Eng. 2021 Mar;11628. doi: 10.1117/12.2583397. Epub 2021 Mar 12.
9
Evaluation of the cumulative Cherenkov converted dose on TSET patients with multiple Cherenkov cameras.使用多个切伦科夫相机对TSET患者累积切伦科夫转换剂量的评估。
Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12359. doi: 10.1117/12.2651177. Epub 2023 Mar 14.
10
Monte Carlo simulation of Cherenkov imaging for Total Skin Electron Treatment with CT DICOM realistic patient geometry.基于CT DICOM真实患者几何结构的全身皮肤电子治疗切伦科夫成像的蒙特卡罗模拟。
Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb;11940. doi: 10.1117/12.2609027. Epub 2022 Mar 4.

引用本文的文献

1
Assessment of generic corrections for multiview Cherenkov emission during total skin electron therapy (TSET).全身皮肤电子线治疗（TSET）期间多视角切伦科夫发射通用校正的评估。
Proc SPIE Int Soc Opt Eng. 2025 Jan;13299. doi: 10.1117/12.3046423. Epub 2025 Mar 19.
2
Real-time dosimetry using scintillator technology in external beam radiation therapy (EBRT).在体外放射治疗（EBRT）中使用闪烁体技术进行实时剂量测定。
Proc SPIE Int Soc Opt Eng. 2025 Jan;13309. doi: 10.1117/12.3048325. Epub 2025 Mar 20.
3
Development and Dosimetric Characterization of a Customizable Shield for Subtotal Skin Electron Beam Therapy.用于部分皮肤电子束治疗的可定制屏蔽罩的开发与剂量学特性研究
Adv Radiat Oncol. 2023 Jun 14;8(6):101289. doi: 10.1016/j.adro.2023.101289. eCollection 2023 Nov-Dec.
4
Evaluation of the cumulative Cherenkov converted dose on TSET patients with multiple Cherenkov cameras.使用多个切伦科夫相机对TSET患者累积切伦科夫转换剂量的评估。
Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12359. doi: 10.1117/12.2651177. Epub 2023 Mar 14.
5
Comparison of surface dose during whole breast radiation therapy on Halcyon and TrueBeam using Cherenkov imaging.使用切伦科夫成像技术比较Halcyon和TrueBeam在全乳放疗期间的表面剂量。
Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12371. doi: 10.1117/12.2652588. Epub 2023 Mar 6.
6
Total Skin Treatment with Helical Arc Radiotherapy.螺旋弧形放射疗法治疗皮肤癌。
Int J Mol Sci. 2023 Feb 24;24(5):4492. doi: 10.3390/ijms24054492.
7
A review of recent and emerging approaches for the clinical application of Cerenkov luminescence imaging.对切伦科夫发光成像临床应用的最新及新兴方法的综述。
Front Phys. 2021;9. doi: 10.3389/fphy.2021.684196. Epub 2021 Jul 28.
8
Computational dose visualization & comparison in total skin electron treatment suggests superior coverage by the rotational versus the Stanford technique.全皮电子束治疗中的计算剂量可视化和比较表明，旋转技术比斯坦福技术具有更好的覆盖范围。
J Med Imaging Radiat Sci. 2022 Dec;53(4):612-622. doi: 10.1016/j.jmir.2022.08.006. Epub 2022 Aug 28.
9
Monte Carlo simulation of Cherenkov imaging for Total Skin Electron Treatment with CT DICOM realistic patient geometry.基于CT DICOM真实患者几何结构的全身皮肤电子治疗切伦科夫成像的蒙特卡罗模拟。
Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb;11940. doi: 10.1117/12.2609027. Epub 2022 Mar 4.
10
Optimization of in vivo Cherenkov imaging dosimetry via spectral choices for ambient background lights and filtering.通过选择环境背景光和滤波进行光谱优化，实现体内切伦科夫成像剂量学。
J Biomed Opt. 2021 Oct;26(10). doi: 10.1117/1.JBO.26.10.106003.

本文引用的文献

1
Assessment of imaging Cherenkov and scintillation signals in head and neck radiotherapy.头颈部放射治疗中 Cherenkov 和闪烁信号的成像评估。
Phys Med Biol. 2019 Jul 18;64(14):145021. doi: 10.1088/1361-6560/ab25a3.
2
Monte Carlo investigation of the effect of skin tissue optical properties on detected Cherenkov emission.皮肤组织光学特性对探测到的切伦科夫辐射影响的蒙特卡罗研究。
Proc SPIE Int Soc Opt Eng. 2019 Feb;10862. doi: 10.1117/12.2509854. Epub 2019 Mar 7.
3
Rapid Multisite Remote Surface Dosimetry for Total Skin Electron Therapy: Scintillator Target Imaging.快速多点远程表面剂量测定在全身皮肤电子治疗中的应用：闪烁体靶成像。
Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):767-774. doi: 10.1016/j.ijrobp.2018.10.030. Epub 2018 Nov 10.
4
Characterization of the Cerenkov scatter function: a convolution kernel for Cerenkov light dosimetry.描述切伦科夫散射线函数：一种适用于切伦科夫光剂量测定的卷积核。
J Biomed Opt. 2018 Oct;23(10):1-12. doi: 10.1117/1.JBO.23.10.105007.
5
A mathematical deconvolution formulation for superficial dose distribution measurement by Cerenkov light dosimetry.一种用于通过切伦科夫光剂量测定法测量表面剂量分布的数学反卷积公式。
Med Phys. 2018 Jun 1. doi: 10.1002/mp.13021.
6
Improving treatment geometries in total skin electron therapy: Experimental investigation of linac angles and floor scatter dose contributions using Cherenkov imaging.提高全身电子治疗中的治疗几何形状：使用切伦科夫成像研究直线加速器角度和地板散射剂量的贡献。
Med Phys. 2018 Jun;45(6):2639-2646. doi: 10.1002/mp.12917. Epub 2018 May 6.
7
Algorithm development for intrafraction radiotherapy beam edge verification from Cherenkov imaging.基于切伦科夫成像的分次放疗束流边缘验证算法开发
J Med Imaging (Bellingham). 2018 Jan;5(1):015001. doi: 10.1117/1.JMI.5.1.015001. Epub 2018 Jan 2.
8
Beam and tissue factors affecting Cherenkov image intensity for quantitative entrance and exit dosimetry on human tissue.影响用于人体组织定量入射和出射剂量测定的切伦科夫图像强度的射束和组织因素。
J Biophotonics. 2017 May;10(5):645-656. doi: 10.1002/jbio.201500344. Epub 2016 Aug 10.
9
Cherenkov imaging method for rapid optimization of clinical treatment geometry in total skin electron beam therapy.用于全身皮肤电子束治疗中临床治疗几何形状快速优化的切伦科夫成像方法。
Med Phys. 2016 Feb;43(2):993-1002. doi: 10.1118/1.4939880.
10
Optical cone beam tomography of Cherenkov-mediated signals for fast 3D dosimetry of x-ray photon beams in water.用于水中X射线光子束快速三维剂量测定的切伦科夫介导信号的光学锥束断层扫描
Med Phys. 2015 Jul;42(7):4127-36. doi: 10.1118/1.4922135.

切伦科夫成像在全身电子束放射治疗（TSET）中的应用。

Cherenkov imaging for total skin electron therapy (TSET).

机构信息

Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, 02114, USA.

出版信息

Med Phys. 2020 Jan;47(1):201-212. doi: 10.1002/mp.13881. Epub 2019 Nov 26.

DOI:10.1002/mp.13881
PMID:31665544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7050296/
Abstract

BACKGROUND

Total skin electron therapy (TSET) utilizes high-energy electrons to treat malignancies on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interactions between the high-energy electron beam and tissue.

METHODS AND MATERIALS

With a time-gated intensified camera system, the Cherenkov emission can be used to evaluate the dose uniformity on the surface of the patient in real time. Fifteen patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed. Each patient was monitored during TSET via in vivo detectors (IVD) in nine locations. For accurate Cherenkov imaging, a comparison between IVD and Cherenkov profiles was conducted using a polyvinyl chloride board to establish the perspective corrections.

RESULTS AND DISCUSSION

With proper corrections developed in this study including the perspective and inverse square corrections, the Cherenkov imaging provided two-dimensional maps proportional to dose and projected on patient skin. The results of ratio between chest and umbilicus points were in good agreement with in vivo point dose measurements, with a standard deviation of 2.4% compared to OSLD measurements.

CONCLUSIONS

Cherenkov imaging is a viable tool for validating patient-specific dose distributions during TSET.

摘要

背景

全身电子疗法（TSET）利用高能电子束治疗整个身体表面的恶性肿瘤。否则不可见的辐射束可以通过高能电子束与组织相互作用产生的光切伦科夫光子来观察。

方法和材料

使用时间门控增强相机系统，可以实时评估患者表面的剂量均匀性。对 15 名接受 TSET 治疗的患者进行了成像和分析，他们处于不同的治疗条件（全身和半身）。每个患者在 TSET 治疗过程中，通过在九个位置使用体内探测器（IVD）进行监测。为了进行准确的切伦科夫成像，使用聚氯乙烯板进行了 IVD 和切伦科夫轮廓之间的比较，以建立透视校正。

结果与讨论

通过本研究中开发的适当校正，包括透视和平方反比校正，切伦科夫成像提供了与剂量成正比并投影到患者皮肤上的二维图谱。与 OSLD 测量相比，胸点和脐点之间的比值结果与体内点剂量测量非常吻合，标准偏差为 2.4%。

结论

切伦科夫成像对于验证 TSET 期间的患者特定剂量分布是一种可行的工具。