增殖性玻璃体视网膜病变的药物治疗
Pharmacological therapy for proliferative vitreoretinopathy.
作者信息
Radtke N D, Weinsieder A D, Ballou R J
出版信息
Graefes Arch Clin Exp Ophthalmol. 1986;224(3):230-3. doi: 10.1007/BF02143060.
PMID:3710177
Abstract
We developed an animal model in the rabbit eye with intravitreally injected heterotransplanted bovine retinal pigment epithelial cells to test a pharmacological agent which would reduce extracellular matrix formation. Results with 20 and 60 micrograms of cis-hydroxyproline showed a 48% decrease in the rate of traction retinal detachments.
摘要
我们通过向兔眼玻璃体内注射异种移植的牛视网膜色素上皮细胞建立了一种动物模型，以测试一种能够减少细胞外基质形成的药物制剂。20微克和60微克顺式羟脯氨酸的实验结果显示，牵引性视网膜脱离的发生率降低了48%。
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