慢性肾脏病患者静脉补铁外渗后的皮肤染色：一例报告
Skin Staining Following Intravenous Iron Extravasation in a Patient With Chronic Kidney Disease: A Case Report.
作者信息
Shi Ruolin, Marin Judith G, Beaulieu Monica
机构信息
Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada.
Nephrology, St. Paul's Hospital, Vancouver, BC, Canada.
出版信息
Can J Kidney Health Dis. 2023 Apr 18;10:20543581231165705. doi: 10.1177/20543581231165705. eCollection 2023.
RATIONALE
Intravenous iron is commonly use in anemia related to chronic kidney disease. Skin staining due to iron extravasation is a rare adverse reaction that can leave a long-term staining of the skin.
PRESENTING CONCERNS OF THE PATIENTS
During iron derisomaltose infusion, patient reported iron extravasation. Five months after the incident, the skin stain related to the extravasation was still present.
DIAGNOSIS
A case of skin staining due to iron derisomaltose extravasation was diagnosed.
INTERVENTIONS/OUTCOMES: She was reviewed by dermatology and laser therapy was offered.
TEACHING POINTS
Patients and clinicians need to be aware of this complication, and protocol needs to be put in place to minimize extravasation and its complication.
理论依据
静脉注射铁剂常用于治疗与慢性肾脏病相关的贫血。铁剂外渗导致的皮肤染色是一种罕见的不良反应，可使皮肤留下长期色素沉着。
患者目前的担忧
在静脉输注去铁胺麦芽糖期间，患者报告发生了铁剂外渗。事件发生五个月后，与外渗相关的皮肤色素沉着仍然存在。
诊断
诊断为去铁胺麦芽糖外渗导致的皮肤染色病例。
干预措施/结果：皮肤科对她进行了检查，并提供了激光治疗。
教学要点
患者和临床医生需要了解这种并发症，并且需要制定方案以尽量减少外渗及其并发症。
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