Semrad N, Watring W, Fu Y S, Hallatt J, Ryoo M, Lagasse L
Gynecol Oncol. 1986 Jun;24(2):230-5. doi: 10.1016/0090-8258(86)90031-4.
Fallopian tube adenocarcinoma is a rare gynecologic tumor that spreads like epithelial ovarian carcinoma. From 1954 to 1982, thirty patients with tubal adenocarcinomas were treated at UCLA and by the Southern California Permanente Medical Group. The mean age was 52 years. Pain, irregular or postmenopausal bleeding, and vaginal discharge were the most common presenting symptoms. Twenty-two had undergone previous pelvic or abdominal surgery. A pelvic mass was the most common physical finding, while Pap smears, IVP, and BE were rarely helpful in making the diagnosis or planning treatment. All of the patients in this report underwent primary therapeutic surgery. Nineteen patients received radiation and fourteen, systemic chemotherapy. Surgical stage was prognostic for survival. Fourteen patients with Stage I and II disease are NED (4 at 2 years; 10 at 5 years). No patients with Stage III or IV disease survived 5 years. Recurrences were noted as late as 6 years after primary therapy and 10 of 14 recurrent sites were extraperitoneal.
输卵管腺癌是一种罕见的妇科肿瘤，其扩散方式与上皮性卵巢癌相似。1954年至1982年期间，加州大学洛杉矶分校（UCLA）和南加州永久医疗集团对30例输卵管腺癌患者进行了治疗。平均年龄为52岁。疼痛、不规则或绝经后出血以及阴道分泌物是最常见的首发症状。22例患者此前接受过盆腔或腹部手术。盆腔肿块是最常见的体格检查发现，而巴氏涂片、静脉肾盂造影（IVP）和钡灌肠（BE）对诊断或治疗方案的制定很少有帮助。本报告中的所有患者均接受了一期治疗性手术。19例患者接受了放疗，14例接受了全身化疗。手术分期对生存有预后意义。14例I期和II期疾病患者无疾病证据（2年时4例；5年时10例）。III期或IV期疾病患者无1例存活5年。复发最早在初次治疗后6年被发现，14个复发部位中有10个位于腹膜外。
