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口服薰衣草疗法对黑猩猩伤口的影响()

The Effects of Oral Lavender Therapy on Wounding in Chimpanzees ().

作者信息

Magden Elizabeth R, Neal Webb Sarah, Lambeth Susan P, Buchl Stephanie J, Schapiro Steven J

机构信息

Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, 650 Cool Water Dr., Bastrop, TX 78602, USA.

出版信息

Animals (Basel). 2023 Apr 18;13(8):1382. doi: 10.3390/ani13081382.

DOI:10.3390/ani13081382
PMID:37106945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10135126/
Abstract

Lavender administration in humans has been shown to promote calmness without the side effects often observed with benzodiazepines. Studies in both humans and rodents have found that ingestion of oral lavender capsules resulted in significantly decreased anxiety. Additionally, mice developed an anti-conflict effect and humans increased socially inclusive behaviors. Given the safety of oral lavender oil and the observed benefits, we administered daily lavender capsules to six chimpanzees who exhibited conflict-instigating behaviors in an effort to further decrease our already low levels of wounding. We compared the total number of wounds in 25 chimpanzees housed with the six lavender-treated chimpanzees in five different social groups (1) prior to administration of daily oral lavender capsules to (2) total wounds during daily oral lavender capsule treatment. We hypothesized that lavender therapy treatment would reduce overall wounding in the social groups. Surprisingly, overall wounding was higher during the lavender treatment period ( = 0.01), yet the percentage of wounds requiring treatment significantly decreased during the lavender therapy period (36% vs. 21%, = 0.02).

摘要

在人类中,薰衣草的使用已被证明能促进平静,且不会产生苯二氮卓类药物常见的副作用。对人类和啮齿动物的研究均发现,口服薰衣草胶囊会显著降低焦虑水平。此外,小鼠产生了抗冲突效应,而人类的社会包容行为有所增加。鉴于口服薰衣草油的安全性以及所观察到的益处,我们给六只表现出引发冲突行为的黑猩猩每日服用薰衣草胶囊,以期进一步降低本就处于低水平的受伤情况。我们比较了五个不同社会群体中与六只接受薰衣草治疗的黑猩猩一起饲养的25只黑猩猩(1)在每日口服薰衣草胶囊之前的伤口总数和(2)每日口服薰衣草胶囊治疗期间的总伤口数。我们假设薰衣草治疗会减少社会群体中的总体受伤情况。令人惊讶的是,在薰衣草治疗期间总体受伤情况更高( = 0.01),但在薰衣草治疗期间需要治疗的伤口百分比显著下降(36% 对 21%, = 0.02)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d043/10135126/96fdd16c8312/animals-13-01382-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d043/10135126/7172ab067063/animals-13-01382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d043/10135126/96fdd16c8312/animals-13-01382-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d043/10135126/7172ab067063/animals-13-01382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d043/10135126/96fdd16c8312/animals-13-01382-g002.jpg

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Naunyn Schmiedebergs Arch Pharmacol. 2023 May;396(5):877-900. doi: 10.1007/s00210-023-02392-x. Epub 2023 Feb 11.
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Annual Phytochemical Variations and Antioxidant Activity within the Aerial Parts of Lavandula angustifolia, an Evergreen Medicinal Plant.常绿药用植物薰衣草地上部分的年度植物化学成分变化及抗氧化活性
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The Effects of Lavender Essential Oil and its Clinical Implications in Dentistry: A Review.
薰衣草精油的作用及其在牙科中的临床意义:综述
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The Effect of Lavender ( L.) on Reducing Labor Pain: A Systematic Review and Meta-Analysis.薰衣草对减轻分娩疼痛的影响:一项系统评价与荟萃分析
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Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid-β neurotoxicity.薰衣草和芫荽精油及其主要成分芳樟醇对淀粉样β神经毒性有保护作用。
Phytother Res. 2021 Jan;35(1):486-493. doi: 10.1002/ptr.6827. Epub 2020 Aug 12.
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Efficacy and safety of lavender essential oil (Silexan) capsules among patients suffering from anxiety disorders: A network meta-analysis.治疗焦虑症患者的薰衣草精油(Silexan)胶囊的疗效和安全性:网络荟萃分析。
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