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[Iodo carboxamidino-1 phenyl-4 piperazine, a new adrenomedullary imaging agent: comparison with metaiodobenzylguanidine].

作者信息

Letiec A, Guilloteau D, Huguet F, Baulieu J L, Besnard J C, Viel C

出版信息

Int J Nucl Med Biol. 1986;12(6):495-6.

PMID:3710709
Abstract

This report describes the comparison between two adrenal medulla imaging agents, mIBG and I-CPP. Biodistribution demonstrated an early and preferential uptake by both adrenal glands and heart and then storage in the adrenal gland of both agents, however I-CPP is less stable in vivo than mIBG. Reserpine depletion study in rat indicated that the I-CPP and mIBG uptake mechanisms are not similar.

摘要

相似文献

1
[Iodo carboxamidino-1 phenyl-4 piperazine, a new adrenomedullary imaging agent: comparison with metaiodobenzylguanidine].
Int J Nucl Med Biol. 1986;12(6):495-6.
2
Evaluation of a new adrenomedullary imaging agent: 131I-meta-iodobenzylguanidine (131I-MIBG). I: Experimental studies on animals.
Rays. 1985 May-Aug;10(2):117-24.
3
Imaging the primate adrenal medulla with [123I] and [131I] meta-iodobenzylguanidine: concise communication.用[123I]和[131I]间碘苄胍对灵长类动物肾上腺髓质进行成像：简要通讯
J Nucl Med. 1981 Apr;22(4):358-64.
4
Meta-iodobenzylguanidine adrenal medulla localization: autoradiographic and pharmacologic studies.间碘苄胍肾上腺髓质定位：放射自显影和药理学研究
Eur J Nucl Med. 1984;9(6):278-81. doi: 10.1007/BF00803250.
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Radiolabeled adrenergi neuron-blocking agents: adrenomedullary imaging with [131I]iodobenzylguanidine.放射性标记的肾上腺素能神经元阻断剂：用[131I]碘苄胍进行肾上腺髓质显像。
J Nucl Med. 1980 Apr;21(4):349-53.
6
[Adrenomedullary scintigraphy with I-131 metaiodobenzylguanidine].
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Quantitation of iodine-123 MIBG uptake by normal adrenal medulla in hypertensive patients.高血压患者正常肾上腺髓质对碘-123间碘苄胍摄取的定量分析。
J Nucl Med. 1987 Mar;28(3):319-24.
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Adrenal medulla imaging agents: a structure-distribution relationship study of radiolabeled aralkylguanidines.
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Radioiodinated 1-carboxamidino-4-phenylpiperazine: a potential adrenal and myocardial imaging radiopharmaceutical.
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