Maynard Adam G, Petrova Boryana, Kanarek Naama
Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA.
Graduate Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.
Metabolites. 2023 Mar 28;13(4):486. doi: 10.3390/metabo13040486.
Here, we present notes from the Folate, Vitamin B12, and One-Carbon Metabolism Conference organized by The Federation of American Societies for Experimental Biology (FASEB), held in Asheville, North Carolina, USA, 14-19 August 2022. We aim to share the most recent findings in the field with members of our scientific community who did not attend the meeting and who are interested in the research that was presented. The research described includes discussions of one-carbon metabolism at the biochemical and physiological levels and studies of the role of folate and B12 in development and in the adult, and from bacteria to mammals. Furthermore, the summarized studies address the role of one-carbon metabolism in disease, including COVID-19, neurodegeneration, and cancer.
在此，我们呈现了2022年8月14日至19日在美国北卡罗来纳州阿什维尔举行的、由美国实验生物学学会联合会（FASEB）组织的叶酸、维生素B12与一碳代谢会议的会议纪要。我们旨在与未参会但对会上所展示研究感兴趣的科学界成员分享该领域的最新发现。所描述的研究包括在生化和生理层面上对一碳代谢的讨论，以及对叶酸和维生素B12在发育过程、成年期以及从细菌到哺乳动物等方面作用的研究。此外，总结的研究还涉及一碳代谢在疾病（包括新冠病毒病、神经退行性变和癌症）中的作用。
