Joffe R T, Post R M, Uhde T W
J Clin Psychiatry. 1986 Jun;47(6):313-4.
The effect of carbamazepine on body weight was studied in 24 patients with affective illness. Carbamazepine caused significant increases in body weight in the depressed but not the manic patients. Furthermore, the weight gain in the depressed patients seemed to be related to the response to treatment. These preliminary findings suggesting that weight gain is related to improvement in depression and not to a direct effect of the drug require further study.
对24例情感性疾病患者研究了卡马西平对体重的影响。卡马西平使抑郁患者的体重显著增加，但对躁狂患者无此作用。此外，抑郁患者的体重增加似乎与治疗反应有关。这些初步研究结果表明体重增加与抑郁症状的改善有关，而非药物的直接作用，这一结论尚需进一步研究。
